Aerobic exercise preconditioning suppresses subcutaneous tumorigenesis via PI3K/AKT-driven metabolic epigenetic reprogramming and immune microenvironment remodeling

Aerobic exercise preconditioning suppresses subcutaneous tumorigenesis via PI3K/AKT-driven metabolic epigenetic reprogramming and immune microenvironment remodeling

It has been widely recognized that aerobic exercise inhibits tumors, and aerobic glycolysis is closely related to tumor development. Whether exercise preconditioning inhibits subcutaneous tumor growth remains unclear. This study aimed to investigate the effect of aerobic exercise preconditioning on...

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Bibliographic Details
Main Authors: Xue Zhang, Yixue Xia, Lingbing Zheng, Lu Cao, Zhengtang Qi, Shuzhe Ding
Format: Article
Language:English
Published: Elsevier 2025-10-01
Series:Experimental Gerontology
Subjects:
Tumor
Aerobic exercise
Glycolysis
PI3K/AKT
Macrophage
Online Access:http://www.sciencedirect.com/science/article/pii/S0531556525001536
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