Adaptively evolved human oral actinomyces‐sourced defensins show therapeutic potential
Abstract The development of eukaryote‐derived antimicrobial peptides as systemically administered drugs has proven a challenging task. Here, we report the first human oral actinomyces‐sourced defensin—actinomycesin—that shows promise for systemic therapy. Actinomycesin and its homologs are only pres...
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| Main Authors: | Shunyi Zhu, Bin Gao, Yoshitaka Umetsu, Steve Peigneur, Ping Li, Shinya Ohki, Jan Tytgat |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Springer Nature
2021-12-01
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| Series: | EMBO Molecular Medicine |
| Subjects: | |
| Online Access: | https://doi.org/10.15252/emmm.202114499 |
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