Features of tissue oxygen metabolism in the traumatic brain injury and diabetes
The paper presents the analysis of tissue oxygen metabolism in traumatic brain injury and diabetes. It was shown an imbalance between systemic oxygen supply and the need for it due to decreased oxygenation of arterial and mixed venous blood, the total content of oxygen in arterial blood, increased...
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| Format: | Article |
| Language: | English |
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Zaporizhzhia State Medical and Pharmaceutical University
2013-08-01
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| Series: | Patologìâ |
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| Online Access: | http://pat.zsmu.edu.ua/article/view/17367/15057 |
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| author | V.M. Meretskyi |
| author_facet | V.M. Meretskyi |
| author_sort | V.M. Meretskyi |
| collection | DOAJ |
| description | The paper presents the analysis of tissue oxygen metabolism in traumatic brain injury and diabetes. It was shown an imbalance between
systemic oxygen supply and the need for it due to decreased oxygenation of arterial and mixed venous blood, the total content of oxygen
in arterial blood, increased levels of methemoglobin, the trend of the degree of pulmonary and hemic hypoxia increase, compensatory
volume increase of cardiac output insuffi cient for satisfactory oxygen delivery in a traumatic brain injury. Under conditions of the TBI
complicated by diabetes, there was more pronounced disturbance in oxygenation of arterial and mixed venous blood with the slowdown
of their recovery due to the participation of pulmonary and hemic hypoxic components. Hemodynamic disturbances in the absence of
growth in cardiac output and oxygen delivery speed changes, leading to destabilization of the oxygen balance, were observed. |
| format | Article |
| id | doaj-art-a496695f63114adba5a9bfb2b4b355a4 |
| institution | DOAJ |
| issn | 2306-8027 2310-1237 |
| language | English |
| publishDate | 2013-08-01 |
| publisher | Zaporizhzhia State Medical and Pharmaceutical University |
| record_format | Article |
| series | Patologìâ |
| spelling | doaj-art-a496695f63114adba5a9bfb2b4b355a42025-08-20T03:18:59ZengZaporizhzhia State Medical and Pharmaceutical UniversityPatologìâ2306-80272310-12372013-08-012404410.14739/2310-1237.2013.2.17367Features of tissue oxygen metabolism in the traumatic brain injury and diabetesV.M. MeretskyiThe paper presents the analysis of tissue oxygen metabolism in traumatic brain injury and diabetes. It was shown an imbalance between systemic oxygen supply and the need for it due to decreased oxygenation of arterial and mixed venous blood, the total content of oxygen in arterial blood, increased levels of methemoglobin, the trend of the degree of pulmonary and hemic hypoxia increase, compensatory volume increase of cardiac output insuffi cient for satisfactory oxygen delivery in a traumatic brain injury. Under conditions of the TBI complicated by diabetes, there was more pronounced disturbance in oxygenation of arterial and mixed venous blood with the slowdown of their recovery due to the participation of pulmonary and hemic hypoxic components. Hemodynamic disturbances in the absence of growth in cardiac output and oxygen delivery speed changes, leading to destabilization of the oxygen balance, were observed.http://pat.zsmu.edu.ua/article/view/17367/15057brain traumadiabetes mellitusoxygentissue metabolism.бtissue metabolism |
| spellingShingle | V.M. Meretskyi Features of tissue oxygen metabolism in the traumatic brain injury and diabetes Patologìâ brain trauma diabetes mellitus oxygen tissue metabolism.б tissue metabolism |
| title | Features of tissue oxygen metabolism in the traumatic brain injury and diabetes |
| title_full | Features of tissue oxygen metabolism in the traumatic brain injury and diabetes |
| title_fullStr | Features of tissue oxygen metabolism in the traumatic brain injury and diabetes |
| title_full_unstemmed | Features of tissue oxygen metabolism in the traumatic brain injury and diabetes |
| title_short | Features of tissue oxygen metabolism in the traumatic brain injury and diabetes |
| title_sort | features of tissue oxygen metabolism in the traumatic brain injury and diabetes |
| topic | brain trauma diabetes mellitus oxygen tissue metabolism.б tissue metabolism |
| url | http://pat.zsmu.edu.ua/article/view/17367/15057 |
| work_keys_str_mv | AT vmmeretskyi featuresoftissueoxygenmetabolisminthetraumaticbraininjuryanddiabetes |