Exploring the therapeutic mechanism of curcumin in spinal cord injury treatment based on network pharmacology, molecular dynamics simulation, and experimental validation

IntroductionCurcumin, a natural active compound derived from plants, is widely used as a pigment across the globe. Research has demonstrated that curcumin possesses neuroprotective properties in spinal cord injuries (SCIs); however, its specific mechanisms of action remain unclear. This study aimed...

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Bibliographic Details
Main Authors: Yongzhi He, Jiachun Lu, Yushan Luo, Rizhao Pang, Xiaoming Hu, Lijuan Ding, Hua Xiao, Yunyun Wang, Wenchun Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-03-01
Series:Frontiers in Chemistry
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Online Access:https://www.frontiersin.org/articles/10.3389/fchem.2025.1568551/full
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