Proteostasis signatures in human diseases.
The protein homeostasis (proteostasis) network maintains the proteome in a functional state. Although this network has been comprehensively mapped, its perturbations in disease remain incompletely characterised. To address this problem, here we define the proteostasis signatures, which represent the...
Saved in:
| Main Authors: | Christine M Lim, Michele Vendruscolo |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2025-06-01
|
| Series: | PLoS Computational Biology |
| Online Access: | https://doi.org/10.1371/journal.pcbi.1013155 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Proteostasis signatures in human diseases
by: Christine M. Lim, et al.
Published: (2025-06-01) -
Hsp70: A Multifunctional Chaperone in Maintaining Proteostasis and Its Implications in Human Disease
by: Manish Kumar Singh, et al.
Published: (2025-03-01) -
Proteostasis failure: at the intersection between aging and Alzheimer’s disease
by: Natalia Poblete, et al.
Published: (2025-11-01) -
Role of Protein Misfolding and Proteostasis Deficiency in Protein Misfolding Diseases and Aging
by: Karina Cuanalo-Contreras, et al.
Published: (2013-01-01) -
Broken Balance: Emerging Cross-Talk Between Proteostasis and Lipostasis in Neurodegenerative Diseases
by: Jessica Tittelmeier, et al.
Published: (2025-06-01)