Long‐term outcomes of children after prenatal exposure to maternal cancer and its treatment
Abstract The incidence of antenatal cancer is increasing, prompting a medical‐ethical evaluation. The International Network on Cancer, Infertility, and Pregnancy (INCIP) was established to study cancer treatment safety during pregnancy and its impact on maternal and child health. Pivotal research ha...
Saved in:
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2024-04-01
|
| Series: | Acta Obstetricia et Gynecologica Scandinavica |
| Subjects: | |
| Online Access: | https://doi.org/10.1111/aogs.14811 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1850115130305544192 |
|---|---|
| author | Evangeline A. Huis in ’t Veld Indra A. Van Assche Frederic Amant |
| author_facet | Evangeline A. Huis in ’t Veld Indra A. Van Assche Frederic Amant |
| author_sort | Evangeline A. Huis in ’t Veld |
| collection | DOAJ |
| description | Abstract The incidence of antenatal cancer is increasing, prompting a medical‐ethical evaluation. The International Network on Cancer, Infertility, and Pregnancy (INCIP) was established to study cancer treatment safety during pregnancy and its impact on maternal and child health. Pivotal research has led to a paradigm shift in clinical management, demonstrating the feasibility and safety of most antenatal oncological treatments. Short‐term outcomes reveal normal growth and cardiac function in the exposed offspring, but caution is advised against first‐trimester chemotherapy. Psychological impact studies highlight the elevated levels of distress in pregnant cancer patients, underscoring the need for personalized information and ongoing psychological support. Long‐term follow‐up studies address gaps in postnatal impacts, while research into specific chemotherapeutic agents continues. Despite generally reassuring outcomes, continued monitoring is crucial, especially in families, such as those where the child was born premature after cancer (treatment) during pregnancy or where mothers are frequently absent due to continued illness or have died from. The ongoing INCIP child follow‐up initiative aims to further elucidate knowledge gaps, emphasizing the importance of large‐scale studies and personalized patient care. |
| format | Article |
| id | doaj-art-a48dbcf5614f445ea07940e9db19fd02 |
| institution | OA Journals |
| issn | 0001-6349 1600-0412 |
| language | English |
| publishDate | 2024-04-01 |
| publisher | Wiley |
| record_format | Article |
| series | Acta Obstetricia et Gynecologica Scandinavica |
| spelling | doaj-art-a48dbcf5614f445ea07940e9db19fd022025-08-20T02:36:39ZengWileyActa Obstetricia et Gynecologica Scandinavica0001-63491600-04122024-04-01103475776010.1111/aogs.14811Long‐term outcomes of children after prenatal exposure to maternal cancer and its treatmentEvangeline A. Huis in ’t Veld0Indra A. Van Assche1Frederic Amant2Center for Gynecological Oncology Netherlands Cancer Institute Amsterdam The NetherlandsDepartment of Development and Regeneration Unit of Woman and Child, KU Leuven Leuven BelgiumCenter for Gynecological Oncology Netherlands Cancer Institute Amsterdam The NetherlandsAbstract The incidence of antenatal cancer is increasing, prompting a medical‐ethical evaluation. The International Network on Cancer, Infertility, and Pregnancy (INCIP) was established to study cancer treatment safety during pregnancy and its impact on maternal and child health. Pivotal research has led to a paradigm shift in clinical management, demonstrating the feasibility and safety of most antenatal oncological treatments. Short‐term outcomes reveal normal growth and cardiac function in the exposed offspring, but caution is advised against first‐trimester chemotherapy. Psychological impact studies highlight the elevated levels of distress in pregnant cancer patients, underscoring the need for personalized information and ongoing psychological support. Long‐term follow‐up studies address gaps in postnatal impacts, while research into specific chemotherapeutic agents continues. Despite generally reassuring outcomes, continued monitoring is crucial, especially in families, such as those where the child was born premature after cancer (treatment) during pregnancy or where mothers are frequently absent due to continued illness or have died from. The ongoing INCIP child follow‐up initiative aims to further elucidate knowledge gaps, emphasizing the importance of large‐scale studies and personalized patient care.https://doi.org/10.1111/aogs.14811antenatal cancercounselingfollow‐uphealthimpactneurocognition |
| spellingShingle | Evangeline A. Huis in ’t Veld Indra A. Van Assche Frederic Amant Long‐term outcomes of children after prenatal exposure to maternal cancer and its treatment Acta Obstetricia et Gynecologica Scandinavica antenatal cancer counseling follow‐up health impact neurocognition |
| title | Long‐term outcomes of children after prenatal exposure to maternal cancer and its treatment |
| title_full | Long‐term outcomes of children after prenatal exposure to maternal cancer and its treatment |
| title_fullStr | Long‐term outcomes of children after prenatal exposure to maternal cancer and its treatment |
| title_full_unstemmed | Long‐term outcomes of children after prenatal exposure to maternal cancer and its treatment |
| title_short | Long‐term outcomes of children after prenatal exposure to maternal cancer and its treatment |
| title_sort | long term outcomes of children after prenatal exposure to maternal cancer and its treatment |
| topic | antenatal cancer counseling follow‐up health impact neurocognition |
| url | https://doi.org/10.1111/aogs.14811 |
| work_keys_str_mv | AT evangelineahuisintveld longtermoutcomesofchildrenafterprenatalexposuretomaternalcanceranditstreatment AT indraavanassche longtermoutcomesofchildrenafterprenatalexposuretomaternalcanceranditstreatment AT fredericamant longtermoutcomesofchildrenafterprenatalexposuretomaternalcanceranditstreatment |