USAGE RATE OF THE UNLICENSED MEDICATIONS IN NEONATOLOGY: DATA OF THE PHARMACO EPIDEMIOLOGICAL RESEARCH

In recent years clinical pharmacologists working in the field of pediatrics all across the world scrutinize the application issues of unlicensed medications among children. Based on the example of a group of patients consisting of 449 premature infants and with the aid of the pharma coepidemiologica...

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Main Authors: A.S. Kolbin, N.P. Shabalov, V.A. Lyubimenko
Format: Article
Language:Russian
Published: Union of pediatricians of Russia 2007-08-01
Series:Педиатрическая фармакология
Online Access:https://www.pedpharma.ru/jour/article/view/699
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author A.S. Kolbin
N.P. Shabalov
V.A. Lyubimenko
author_facet A.S. Kolbin
N.P. Shabalov
V.A. Lyubimenko
author_sort A.S. Kolbin
collection DOAJ
description In recent years clinical pharmacologists working in the field of pediatrics all across the world scrutinize the application issues of unlicensed medications among children. Based on the example of a group of patients consisting of 449 premature infants and with the aid of the pharma coepidemiological research, the authors showed the usage rate of unlicensed anti infectious medications in neonatology. The analysis embraced the 9 year long period of work of the largest neonatal center in northwest. As a result they uncovered that the anti infectious medications which were prescribed most often were aminoglycoside and cephalosporin antibiotics. The applied medications were referred to the unlicensed in neonatology in 21% of cases, and in 8% of cases they were used off label. Further more, it was noted that there was a general trend towards the considerable increase of application of the banned medications for the analyzed period.Key words: very low birth infants, unlicensed drugs.
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publisher Union of pediatricians of Russia
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series Педиатрическая фармакология
spelling doaj-art-a48b9da054e946d792414b8e497c212e2025-08-20T03:23:02ZrusUnion of pediatricians of RussiaПедиатрическая фармакология1727-57762500-30892007-08-01443540695USAGE RATE OF THE UNLICENSED MEDICATIONS IN NEONATOLOGY: DATA OF THE PHARMACO EPIDEMIOLOGICAL RESEARCHA.S. Kolbin0N.P. Shabalov1V.A. Lyubimenko2Laboratory of Clinical Pharmacology, Medical Therapeutic Study and Scientific Center, Saint Petersburg State University Saint Petersburg State Pediatric Medical AcademySaint Petersburg State Pediatric Medical Academy1st Children's City Hospital, Saint Petersburg, RussiaIn recent years clinical pharmacologists working in the field of pediatrics all across the world scrutinize the application issues of unlicensed medications among children. Based on the example of a group of patients consisting of 449 premature infants and with the aid of the pharma coepidemiological research, the authors showed the usage rate of unlicensed anti infectious medications in neonatology. The analysis embraced the 9 year long period of work of the largest neonatal center in northwest. As a result they uncovered that the anti infectious medications which were prescribed most often were aminoglycoside and cephalosporin antibiotics. The applied medications were referred to the unlicensed in neonatology in 21% of cases, and in 8% of cases they were used off label. Further more, it was noted that there was a general trend towards the considerable increase of application of the banned medications for the analyzed period.Key words: very low birth infants, unlicensed drugs.https://www.pedpharma.ru/jour/article/view/699
spellingShingle A.S. Kolbin
N.P. Shabalov
V.A. Lyubimenko
USAGE RATE OF THE UNLICENSED MEDICATIONS IN NEONATOLOGY: DATA OF THE PHARMACO EPIDEMIOLOGICAL RESEARCH
Педиатрическая фармакология
title USAGE RATE OF THE UNLICENSED MEDICATIONS IN NEONATOLOGY: DATA OF THE PHARMACO EPIDEMIOLOGICAL RESEARCH
title_full USAGE RATE OF THE UNLICENSED MEDICATIONS IN NEONATOLOGY: DATA OF THE PHARMACO EPIDEMIOLOGICAL RESEARCH
title_fullStr USAGE RATE OF THE UNLICENSED MEDICATIONS IN NEONATOLOGY: DATA OF THE PHARMACO EPIDEMIOLOGICAL RESEARCH
title_full_unstemmed USAGE RATE OF THE UNLICENSED MEDICATIONS IN NEONATOLOGY: DATA OF THE PHARMACO EPIDEMIOLOGICAL RESEARCH
title_short USAGE RATE OF THE UNLICENSED MEDICATIONS IN NEONATOLOGY: DATA OF THE PHARMACO EPIDEMIOLOGICAL RESEARCH
title_sort usage rate of the unlicensed medications in neonatology data of the pharmaco epidemiological research
url https://www.pedpharma.ru/jour/article/view/699
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AT npshabalov usagerateoftheunlicensedmedicationsinneonatologydataofthepharmacoepidemiologicalresearch
AT valyubimenko usagerateoftheunlicensedmedicationsinneonatologydataofthepharmacoepidemiologicalresearch