Epidemiological Features of Pandemic Influenza in Kyrgyzstan due to Influenza A(H1N1)pdm

Relevance. Virological laboratory of the Department of prevention of diseases and Sanitary Inspection Healthcare Ministry f of the Kyrgyz Republic is nominated as the National Centre for Influenza Surveillance and accreditated by WHO, and in 2009 is included into a global network of influenza Goal....

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Main Authors: K. T. Kasymbekova, Z. S. Nurmatov, A. B. Komissarov, A. V. Fadeev, D. V. Pereyaslov, L. S. Karpova, G. N. Saparova
Format: Article
Language:Russian
Published: Numikom LLC 2016-10-01
Series:Эпидемиология и вакцинопрофилактика
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Online Access:https://www.epidemvac.ru/jour/article/view/355
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author K. T. Kasymbekova
Z. S. Nurmatov
A. B. Komissarov
A. V. Fadeev
D. V. Pereyaslov
L. S. Karpova
G. N. Saparova
author_facet K. T. Kasymbekova
Z. S. Nurmatov
A. B. Komissarov
A. V. Fadeev
D. V. Pereyaslov
L. S. Karpova
G. N. Saparova
author_sort K. T. Kasymbekova
collection DOAJ
description Relevance. Virological laboratory of the Department of prevention of diseases and Sanitary Inspection Healthcare Ministry f of the Kyrgyz Republic is nominated as the National Centre for Influenza Surveillance and accreditated by WHO, and in 2009 is included into a global network of influenza Goal. The purpose of this study - Assessment of epidemic features of manifestations of pandemic influenza A (H1N1) pdm09 in 2009 on the territory of the Kyrgyz Republic, as a comparative study of the molecular and genetic characteristics of influenza A virus (H1N1) pdm09, circulating on the territory of the Republic and the influenza virus reference strains recommended WHO for inclusion in the vaccine for the northern hemisphere. Materials and methods. On the basis of long-term retrospective analysis of the incidence of influenza and severe acute respiratory infections (SARI), and sentinel epidemiological surveillance (SS) data studied pandemic especially in Kyrgyzstan due to influenza A(H1N1)pdm09. Comparative molecular genetic characteristics of influenza viruses A(H1N1)pdm09 allocated in Kyrgyzstan, with reference strains recommended by the World Health Organization (WHO) for inclusion in the vaccine. Results. Overall, the analysis of the results of laboratory tests carried out as part of the routine and sentinel surveillance showed that from January 2009 to March 2010 at 38.8% of those surveyed from among, influenza viruses (at 655 out of 1687) were found. From January to April 2009 in the main circulating influenza A virus (H3N2), which accounted for 55.9 - 77.9% of the number of positive findings. Seasonal influenza A virus (H1N1) was detected in January - February (35.3 and 13.4%, respectively). The share of the flu virus in January accounted for 8%, in March-April - 25%. Not typeable influenza A virus was detected in February in 8.7% of cases. Conclusions. The results of the molecular genetic and virological studies have shown that the influenza pandemic in 2009 in the Republic was due to the spread of pandemic influenza virus A (H1N1) pdm09.
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spelling doaj-art-a48a6754701e4bc097b7297a40e64ec32025-08-20T03:43:46ZrusNumikom LLCЭпидемиология и вакцинопрофилактика2073-30462619-04942016-10-01155303710.31631/2073-3046-2016-15-5-30-37354Epidemiological Features of Pandemic Influenza in Kyrgyzstan due to Influenza A(H1N1)pdmK. T. Kasymbekova0Z. S. Nurmatov1A. B. Komissarov2A. V. Fadeev3D. V. Pereyaslov4L. S. Karpova5G. N. Saparova6Kyrgyzsky State Medical Institute of retraining and advanced trainingKyrgyzsky State Medical Institute of retraining and advanced trainingThe Federal State Budgetary Institution «Research Influenza Institute» of Ministry of Healthcare of the Russian FederationThe Federal State Budgetary Institution «Research Influenza Institute» of Ministry of Healthcare of the Russian FederationEvropeyskoe Bureau of the World Health OrganizationThe Federal State Budgetary Institution «Research Influenza Institute» of Ministry of Healthcare of the Russian FederationDepartament disease prevention and Sanitary Inspection Ministry of Health The Kyrgyz RepublicRelevance. Virological laboratory of the Department of prevention of diseases and Sanitary Inspection Healthcare Ministry f of the Kyrgyz Republic is nominated as the National Centre for Influenza Surveillance and accreditated by WHO, and in 2009 is included into a global network of influenza Goal. The purpose of this study - Assessment of epidemic features of manifestations of pandemic influenza A (H1N1) pdm09 in 2009 on the territory of the Kyrgyz Republic, as a comparative study of the molecular and genetic characteristics of influenza A virus (H1N1) pdm09, circulating on the territory of the Republic and the influenza virus reference strains recommended WHO for inclusion in the vaccine for the northern hemisphere. Materials and methods. On the basis of long-term retrospective analysis of the incidence of influenza and severe acute respiratory infections (SARI), and sentinel epidemiological surveillance (SS) data studied pandemic especially in Kyrgyzstan due to influenza A(H1N1)pdm09. Comparative molecular genetic characteristics of influenza viruses A(H1N1)pdm09 allocated in Kyrgyzstan, with reference strains recommended by the World Health Organization (WHO) for inclusion in the vaccine. Results. Overall, the analysis of the results of laboratory tests carried out as part of the routine and sentinel surveillance showed that from January 2009 to March 2010 at 38.8% of those surveyed from among, influenza viruses (at 655 out of 1687) were found. From January to April 2009 in the main circulating influenza A virus (H3N2), which accounted for 55.9 - 77.9% of the number of positive findings. Seasonal influenza A virus (H1N1) was detected in January - February (35.3 and 13.4%, respectively). The share of the flu virus in January accounted for 8%, in March-April - 25%. Not typeable influenza A virus was detected in February in 8.7% of cases. Conclusions. The results of the molecular genetic and virological studies have shown that the influenza pandemic in 2009 in the Republic was due to the spread of pandemic influenza virus A (H1N1) pdm09.https://www.epidemvac.ru/jour/article/view/355кыргызстанмолекулярно-генетическая характеристика вирусов гриппа а(h1n1)pdm09референс штаммыпандемический гриппkyrgyzstanmolecular genetic characteristics of influenza viruses a(h1n1)pdm09reference strains of pandemic influenza
spellingShingle K. T. Kasymbekova
Z. S. Nurmatov
A. B. Komissarov
A. V. Fadeev
D. V. Pereyaslov
L. S. Karpova
G. N. Saparova
Epidemiological Features of Pandemic Influenza in Kyrgyzstan due to Influenza A(H1N1)pdm
Эпидемиология и вакцинопрофилактика
кыргызстан
молекулярно-генетическая характеристика вирусов гриппа а(h1n1)pdm09
референс штаммы
пандемический грипп
kyrgyzstan
molecular genetic characteristics of influenza viruses a(h1n1)pdm09
reference strains of pandemic influenza
title Epidemiological Features of Pandemic Influenza in Kyrgyzstan due to Influenza A(H1N1)pdm
title_full Epidemiological Features of Pandemic Influenza in Kyrgyzstan due to Influenza A(H1N1)pdm
title_fullStr Epidemiological Features of Pandemic Influenza in Kyrgyzstan due to Influenza A(H1N1)pdm
title_full_unstemmed Epidemiological Features of Pandemic Influenza in Kyrgyzstan due to Influenza A(H1N1)pdm
title_short Epidemiological Features of Pandemic Influenza in Kyrgyzstan due to Influenza A(H1N1)pdm
title_sort epidemiological features of pandemic influenza in kyrgyzstan due to influenza a h1n1 pdm
topic кыргызстан
молекулярно-генетическая характеристика вирусов гриппа а(h1n1)pdm09
референс штаммы
пандемический грипп
kyrgyzstan
molecular genetic characteristics of influenza viruses a(h1n1)pdm09
reference strains of pandemic influenza
url https://www.epidemvac.ru/jour/article/view/355
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