Chemotherapy resumption in breast cancer patient after COVID-19

Abstract Background While many studies have verified the effect of recent anti-cancer treatment in patients with COVID-19, there are no data on the optimal time for cancer treatment resumption, as well as the safety of chemotherapy in COVID-19 patients. As many cancer patients are recovering from CO...

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Main Authors: Julian Horiguchi, Ayako Nakashoji, Naoki Kawahara, Akira Matsui, Takayuki Kinoshita
Format: Article
Language:English
Published: Japan Surgical Society 2021-07-01
Series:Surgical Case Reports
Subjects:
Online Access:https://doi.org/10.1186/s40792-021-01253-0
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author Julian Horiguchi
Ayako Nakashoji
Naoki Kawahara
Akira Matsui
Takayuki Kinoshita
author_facet Julian Horiguchi
Ayako Nakashoji
Naoki Kawahara
Akira Matsui
Takayuki Kinoshita
author_sort Julian Horiguchi
collection DOAJ
description Abstract Background While many studies have verified the effect of recent anti-cancer treatment in patients with COVID-19, there are no data on the optimal time for cancer treatment resumption, as well as the safety of chemotherapy in COVID-19 patients. As many cancer patients are recovering from COVID-19, there is an urgent need for reliable clinical information. Herein, we report a case of invasive ductal carcinoma in which we were able to successfully resume chemotherapy after infection with SAR-CoV-2. Case presentation The patient was a 38-year-old non-smoking Japanese woman with no significant medical history. She had fever on days 5 and 6 of her second course of adjuvant FEC therapy, and on day 7, she tested positive for SARS-CoV-2 by RT-PCR. She was hospitalized for 11 days. We resumed the therapy on day 25 after discharge, as she had no remaining clinical symptoms. The patient completed four courses of the initial chemotherapy without any major adverse events nor the recurrence of COVID-19, and subsequently completed four courses of docetaxel as her second regimen therapy. Conclusions Evaluating the risk for each patient is essential when resuming anti-cancer therapy in cancer patient’s post-COVID-19.
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spelling doaj-art-a489696203e347bcbf10ff1ca060c8c82025-08-20T03:56:55ZengJapan Surgical SocietySurgical Case Reports2198-77932021-07-01711510.1186/s40792-021-01253-0Chemotherapy resumption in breast cancer patient after COVID-19Julian Horiguchi0Ayako Nakashoji1Naoki Kawahara2Akira Matsui3Takayuki Kinoshita4Department of Surgery, National Hospital Organization Tokyo Medical CenterDepartment of Breast Surgery, National Hospital Organization Tokyo Medical CenterDepartment of Surgery, National Hospital Organization Tokyo Medical CenterDepartment of Breast Surgery, National Hospital Organization Tokyo Medical CenterDepartment of Breast Surgery, National Hospital Organization Tokyo Medical CenterAbstract Background While many studies have verified the effect of recent anti-cancer treatment in patients with COVID-19, there are no data on the optimal time for cancer treatment resumption, as well as the safety of chemotherapy in COVID-19 patients. As many cancer patients are recovering from COVID-19, there is an urgent need for reliable clinical information. Herein, we report a case of invasive ductal carcinoma in which we were able to successfully resume chemotherapy after infection with SAR-CoV-2. Case presentation The patient was a 38-year-old non-smoking Japanese woman with no significant medical history. She had fever on days 5 and 6 of her second course of adjuvant FEC therapy, and on day 7, she tested positive for SARS-CoV-2 by RT-PCR. She was hospitalized for 11 days. We resumed the therapy on day 25 after discharge, as she had no remaining clinical symptoms. The patient completed four courses of the initial chemotherapy without any major adverse events nor the recurrence of COVID-19, and subsequently completed four courses of docetaxel as her second regimen therapy. Conclusions Evaluating the risk for each patient is essential when resuming anti-cancer therapy in cancer patient’s post-COVID-19.https://doi.org/10.1186/s40792-021-01253-0COVID-19Severe acute respiratory syndrome coronavirus 2ResumptionBreast cancerChemotherapyCase report
spellingShingle Julian Horiguchi
Ayako Nakashoji
Naoki Kawahara
Akira Matsui
Takayuki Kinoshita
Chemotherapy resumption in breast cancer patient after COVID-19
Surgical Case Reports
COVID-19
Severe acute respiratory syndrome coronavirus 2
Resumption
Breast cancer
Chemotherapy
Case report
title Chemotherapy resumption in breast cancer patient after COVID-19
title_full Chemotherapy resumption in breast cancer patient after COVID-19
title_fullStr Chemotherapy resumption in breast cancer patient after COVID-19
title_full_unstemmed Chemotherapy resumption in breast cancer patient after COVID-19
title_short Chemotherapy resumption in breast cancer patient after COVID-19
title_sort chemotherapy resumption in breast cancer patient after covid 19
topic COVID-19
Severe acute respiratory syndrome coronavirus 2
Resumption
Breast cancer
Chemotherapy
Case report
url https://doi.org/10.1186/s40792-021-01253-0
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AT naokikawahara chemotherapyresumptioninbreastcancerpatientaftercovid19
AT akiramatsui chemotherapyresumptioninbreastcancerpatientaftercovid19
AT takayukikinoshita chemotherapyresumptioninbreastcancerpatientaftercovid19