A study of neuroprotective effect stereospecificity of dipeptide mimetic of the Brain-derived neurotrophic factor GSB-106 on the model oxidative stress in the culture hippocampal cell line HT-22

A study of neuroprotective effect stereospecificity of dipeptide mimetic of the Brain-derived neurotrophic factor GSB-106 on the model oxidative stress in the culture hippocampal cell line HT-22

In the present work, the neuroprotective effect stereospecificity of dimeric dipeptide mimetic of the 4th loop of BDNF-GSB-106 is studied. Activity of its diastereomers GT-106DL (hexamethylenediamide bis-monosuccinyl-D-seryl-L-lysine) and GT-106LD (hexamethylenediamide bis-monosuccinyl-L-seryl-D-lys...

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Bibliographic Details
Main Authors: I. O. Logvinov, A. V. Tarasiuk, P. I. Antipov, T. A. Antipova
Format: Article
Language:Russian
Published: LLC “Publisher OKI” 2017-07-01
Series:Фармакокинетика и Фармакодинамика
Subjects:
нейропротекция
оксидативный стресс
bdnf
гсб-106
стереоспецифичность
neuroprotection
oxidative stress
gsb-106
stereospecificity
Online Access:https://www.pharmacokinetica.ru/jour/article/view/24
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