Assessment Of COVID-19 Positive Patients With ST-Segment Elevation Myocardial Infarction During The COVID-19 Pandemic
Objective: The global impact of the coronavirus disease 2019 (COVID-19) pandemic has been shown to adversely affect the cardiovascular system. Investigating the clinical course of patients with ST-segment elevation myocardial infarction (STEMI) associated with COVID-19 infection is crucial to elucid...
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Atatürk University
2025-04-01
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| Series: | Journal of Medical Education and Family Medicine |
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| Online Access: | https://dergipark.org.tr/en/download/article-file/4257535 |
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| author | Hakan Duman Handan Duman |
| author_facet | Hakan Duman Handan Duman |
| author_sort | Hakan Duman |
| collection | DOAJ |
| description | Objective: The global impact of the coronavirus disease 2019 (COVID-19) pandemic has been shown to adversely affect the cardiovascular system. Investigating the clinical course of patients with ST-segment elevation myocardial infarction (STEMI) associated with COVID-19 infection is crucial to elucidate the mechanisms linking COVID-19 and STEMI. Assessing these patients from both cardiovascular and infection control perspectives is essential for improving clinical outcomes and reducing the burden on healthcare systems. This study aims to provide a comprehensive evaluation of the clinical course of COVID-19-positive STEMI patients.Methods: This single-center, cross-sectional study analyzed 80 STEMI patients who underwent coronary angiography, comprising 38 COVID-19-positive individuals and 42 COVID-19-negative individuals. We assessed admission times, biochemical parameters, door-to-balloon times, angiographic data, length of hospital stay, and in-hospital mortality.Results: The mean age in the COVID-19-positive group was 56.6±10.8 years, whereas that in the COVID-19-negative group was 53.6±10.8 years (P = .238). No significant differences in demographic characteristics were observed between the groups. However, C-reactive protein (CRP), white blood cell (WBC), and baseline troponin levels were significantly greater in the COVID-19-positive group (P < .001, P = .005, and P = .037, respectively). Echocardiographic evaluation revealed a lower ejection fraction (EF) in COVID-19-positive patients than in COVID-19-negative patients (P = .023). Angiographic evaluation revealed a greater thrombus burden and longer pain-to-balloon time in the COVID-19-positive group (P = .001 and P < .001, respectively). The length of hospital stay was also longer in the COVID-19-positive group (P < .001).Conclusion: The findings of increased thrombus burden, prolonged pain-to-balloon time, and extended hospital stays among COVID-19-positive patients underscore the adverse cardiovascular effects of COVID-19. Delayed hospital presentation of patients with cardiovascular symptoms during the pandemic poses a challenge for timely diagnosis and management of critical cardiovascular conditions. |
| format | Article |
| id | doaj-art-a471ff70ef464059855014febdec2342 |
| institution | Kabale University |
| issn | 3023-7793 |
| language | English |
| publishDate | 2025-04-01 |
| publisher | Atatürk University |
| record_format | Article |
| series | Journal of Medical Education and Family Medicine |
| spelling | doaj-art-a471ff70ef464059855014febdec23422025-08-20T03:53:42ZengAtatürk UniversityJournal of Medical Education and Family Medicine3023-77932025-04-0121222710.62425/jmefm.155990155Assessment Of COVID-19 Positive Patients With ST-Segment Elevation Myocardial Infarction During The COVID-19 PandemicHakan Duman0https://orcid.org/0000-0002-1441-7320Handan Duman1https://orcid.org/0000-0002-9519-8739RECEP TAYYIP ERDOGAN UNIVERSITYRECEP TAYYIP ERDOGAN UNIVERSITYObjective: The global impact of the coronavirus disease 2019 (COVID-19) pandemic has been shown to adversely affect the cardiovascular system. Investigating the clinical course of patients with ST-segment elevation myocardial infarction (STEMI) associated with COVID-19 infection is crucial to elucidate the mechanisms linking COVID-19 and STEMI. Assessing these patients from both cardiovascular and infection control perspectives is essential for improving clinical outcomes and reducing the burden on healthcare systems. This study aims to provide a comprehensive evaluation of the clinical course of COVID-19-positive STEMI patients.Methods: This single-center, cross-sectional study analyzed 80 STEMI patients who underwent coronary angiography, comprising 38 COVID-19-positive individuals and 42 COVID-19-negative individuals. We assessed admission times, biochemical parameters, door-to-balloon times, angiographic data, length of hospital stay, and in-hospital mortality.Results: The mean age in the COVID-19-positive group was 56.6±10.8 years, whereas that in the COVID-19-negative group was 53.6±10.8 years (P = .238). No significant differences in demographic characteristics were observed between the groups. However, C-reactive protein (CRP), white blood cell (WBC), and baseline troponin levels were significantly greater in the COVID-19-positive group (P < .001, P = .005, and P = .037, respectively). Echocardiographic evaluation revealed a lower ejection fraction (EF) in COVID-19-positive patients than in COVID-19-negative patients (P = .023). Angiographic evaluation revealed a greater thrombus burden and longer pain-to-balloon time in the COVID-19-positive group (P = .001 and P < .001, respectively). The length of hospital stay was also longer in the COVID-19-positive group (P < .001).Conclusion: The findings of increased thrombus burden, prolonged pain-to-balloon time, and extended hospital stays among COVID-19-positive patients underscore the adverse cardiovascular effects of COVID-19. Delayed hospital presentation of patients with cardiovascular symptoms during the pandemic poses a challenge for timely diagnosis and management of critical cardiovascular conditions.https://dergipark.org.tr/en/download/article-file/4257535covid-19stemithrombus burden |
| spellingShingle | Hakan Duman Handan Duman Assessment Of COVID-19 Positive Patients With ST-Segment Elevation Myocardial Infarction During The COVID-19 Pandemic Journal of Medical Education and Family Medicine covid-19 stemi thrombus burden |
| title | Assessment Of COVID-19 Positive Patients With ST-Segment Elevation Myocardial Infarction During The COVID-19 Pandemic |
| title_full | Assessment Of COVID-19 Positive Patients With ST-Segment Elevation Myocardial Infarction During The COVID-19 Pandemic |
| title_fullStr | Assessment Of COVID-19 Positive Patients With ST-Segment Elevation Myocardial Infarction During The COVID-19 Pandemic |
| title_full_unstemmed | Assessment Of COVID-19 Positive Patients With ST-Segment Elevation Myocardial Infarction During The COVID-19 Pandemic |
| title_short | Assessment Of COVID-19 Positive Patients With ST-Segment Elevation Myocardial Infarction During The COVID-19 Pandemic |
| title_sort | assessment of covid 19 positive patients with st segment elevation myocardial infarction during the covid 19 pandemic |
| topic | covid-19 stemi thrombus burden |
| url | https://dergipark.org.tr/en/download/article-file/4257535 |
| work_keys_str_mv | AT hakanduman assessmentofcovid19positivepatientswithstsegmentelevationmyocardialinfarctionduringthecovid19pandemic AT handanduman assessmentofcovid19positivepatientswithstsegmentelevationmyocardialinfarctionduringthecovid19pandemic |