Acute necrotic disorder of the small intestine post‐coronavirus disease‐2019 vaccination
Abstract The Pfizer‐BioNTech coronavirus disease 2019 (COVID‐19) vaccine is extensively used worldwide, and its safety has been proven. Herein, we report a case of an acute necrotic disorder in the small intestine post‐COVID‐19 vaccination. The patient developed severe abdominal pain the day after t...
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| Format: | Article |
| Language: | English |
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Wiley
2023-04-01
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| Series: | DEN Open |
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| Online Access: | https://doi.org/10.1002/deo2.137 |
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| author | Tomoyuki Nishimura Seiji Onogawa Takuya Yamamoto Yasuhiro Okuda Morito Ikeda Nozomu Matsumoto Keisuke Kurihara Akinori Shimizu Shosuke Kitamura Yoshio Katamura Naomichi Hirano Shingo Itamoto Masahiro Nakahara Shuji Yonehara Fumio Shimamoto Keiji Hanada |
| author_facet | Tomoyuki Nishimura Seiji Onogawa Takuya Yamamoto Yasuhiro Okuda Morito Ikeda Nozomu Matsumoto Keisuke Kurihara Akinori Shimizu Shosuke Kitamura Yoshio Katamura Naomichi Hirano Shingo Itamoto Masahiro Nakahara Shuji Yonehara Fumio Shimamoto Keiji Hanada |
| author_sort | Tomoyuki Nishimura |
| collection | DOAJ |
| description | Abstract The Pfizer‐BioNTech coronavirus disease 2019 (COVID‐19) vaccine is extensively used worldwide, and its safety has been proven. Herein, we report a case of an acute necrotic disorder in the small intestine post‐COVID‐19 vaccination. The patient developed severe abdominal pain the day after the first vaccination. Contrast‐enhanced computed tomography showed extensive ileum wall thickening and ascites. Colonoscopy revealed a ring‐shaped ulcer and stricture in the terminal ileum. Ileocecal resection was performed, and the patient did not have further episodes of a necrotic disorder in the small intestine. Although it is unknown if this event is associated with vaccination, and this occurrence also does not outweigh the efficacy and safety of the Pfizer‐BioNTech COVID‐19 vaccine, gastroenterologists need to be aware of this rare case, given its noteworthy timing. |
| format | Article |
| id | doaj-art-a46cecdc4c2e491dbbf4f47221ac9145 |
| institution | Kabale University |
| issn | 2692-4609 |
| language | English |
| publishDate | 2023-04-01 |
| publisher | Wiley |
| record_format | Article |
| series | DEN Open |
| spelling | doaj-art-a46cecdc4c2e491dbbf4f47221ac91452025-08-20T03:49:41ZengWileyDEN Open2692-46092023-04-0131n/an/a10.1002/deo2.137Acute necrotic disorder of the small intestine post‐coronavirus disease‐2019 vaccinationTomoyuki Nishimura0Seiji Onogawa1Takuya Yamamoto2Yasuhiro Okuda3Morito Ikeda4Nozomu Matsumoto5Keisuke Kurihara6Akinori Shimizu7Shosuke Kitamura8Yoshio Katamura9Naomichi Hirano10Shingo Itamoto11Masahiro Nakahara12Shuji Yonehara13Fumio Shimamoto14Keiji Hanada15Department of Gastroenterology Onomichi General Hospital Hiroshima JapanDepartment of Gastroenterology Onomichi General Hospital Hiroshima JapanDepartment of Gastroenterology Onomichi General Hospital Hiroshima JapanDepartment of Gastroenterology Onomichi General Hospital Hiroshima JapanDepartment of Gastroenterology Onomichi General Hospital Hiroshima JapanDepartment of Gastroenterology Onomichi General Hospital Hiroshima JapanDepartment of Gastroenterology Onomichi General Hospital Hiroshima JapanDepartment of Gastroenterology Onomichi General Hospital Hiroshima JapanDepartment of Gastroenterology Onomichi General Hospital Hiroshima JapanDepartment of Gastroenterology Onomichi General Hospital Hiroshima JapanDepartment of Gastroenterology Onomichi General Hospital Hiroshima JapanDepartment of Surgery Onomichi General Hospital Hiroshima JapanDepartment of Surgery Onomichi General Hospital Hiroshima JapanDepartment of Pathology Onomichi General Hospital Hiroshima JapanDepartment of Nursing Faculty of Health Sciences Hiroshima Cosmopolitan University Hiroshima JapanDepartment of Gastroenterology Onomichi General Hospital Hiroshima JapanAbstract The Pfizer‐BioNTech coronavirus disease 2019 (COVID‐19) vaccine is extensively used worldwide, and its safety has been proven. Herein, we report a case of an acute necrotic disorder in the small intestine post‐COVID‐19 vaccination. The patient developed severe abdominal pain the day after the first vaccination. Contrast‐enhanced computed tomography showed extensive ileum wall thickening and ascites. Colonoscopy revealed a ring‐shaped ulcer and stricture in the terminal ileum. Ileocecal resection was performed, and the patient did not have further episodes of a necrotic disorder in the small intestine. Although it is unknown if this event is associated with vaccination, and this occurrence also does not outweigh the efficacy and safety of the Pfizer‐BioNTech COVID‐19 vaccine, gastroenterologists need to be aware of this rare case, given its noteworthy timing.https://doi.org/10.1002/deo2.137COVID‐19necrosisside effectssmall intestinevaccines |
| spellingShingle | Tomoyuki Nishimura Seiji Onogawa Takuya Yamamoto Yasuhiro Okuda Morito Ikeda Nozomu Matsumoto Keisuke Kurihara Akinori Shimizu Shosuke Kitamura Yoshio Katamura Naomichi Hirano Shingo Itamoto Masahiro Nakahara Shuji Yonehara Fumio Shimamoto Keiji Hanada Acute necrotic disorder of the small intestine post‐coronavirus disease‐2019 vaccination DEN Open COVID‐19 necrosis side effects small intestine vaccines |
| title | Acute necrotic disorder of the small intestine post‐coronavirus disease‐2019 vaccination |
| title_full | Acute necrotic disorder of the small intestine post‐coronavirus disease‐2019 vaccination |
| title_fullStr | Acute necrotic disorder of the small intestine post‐coronavirus disease‐2019 vaccination |
| title_full_unstemmed | Acute necrotic disorder of the small intestine post‐coronavirus disease‐2019 vaccination |
| title_short | Acute necrotic disorder of the small intestine post‐coronavirus disease‐2019 vaccination |
| title_sort | acute necrotic disorder of the small intestine post coronavirus disease 2019 vaccination |
| topic | COVID‐19 necrosis side effects small intestine vaccines |
| url | https://doi.org/10.1002/deo2.137 |
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