Peyronie's Disease: Evolving Surgical Management and the Role of Phosphodiesterase 5 Inhibitors
Peyronie's disease (PD) is a fibrotic disorder of the tunica albuginea of the penis. It is characterized by different degrees of penile curvature and sexual dysfunction. Several medical treatments have been employed to manage the disorder, with variable success rates. Surgical therapy is reserv...
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| Format: | Article |
| Language: | English |
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Wiley
2009-01-01
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| Series: | The Scientific World Journal |
| Online Access: | http://dx.doi.org/10.1100/tsw.2009.101 |
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| _version_ | 1832561786882097152 |
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| author | Tariq F. Al-Shaiji Gerald B. Brock |
| author_facet | Tariq F. Al-Shaiji Gerald B. Brock |
| author_sort | Tariq F. Al-Shaiji |
| collection | DOAJ |
| description | Peyronie's disease (PD) is a fibrotic disorder of the tunica albuginea of the penis. It is characterized by different degrees of penile curvature and sexual dysfunction. Several medical treatments have been employed to manage the disorder, with variable success rates. Surgical therapy is reserved for patients with severe penile deformity that fails to improve with medical treatment and impedes coital function. The advantages and disadvantages of various surgical approaches have long been debated. Herein, we describe the evolving surgical techniques for PD using knowledge obtained from the contemporary literature. In addition, we discuss the emerging data regarding the role of phosphodiesterase 5 inhibitors in the management of PD. |
| format | Article |
| id | doaj-art-a4675f7e511840fdb9ded3b077c16531 |
| institution | Kabale University |
| issn | 1537-744X |
| language | English |
| publishDate | 2009-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | The Scientific World Journal |
| spelling | doaj-art-a4675f7e511840fdb9ded3b077c165312025-02-03T01:24:16ZengWileyThe Scientific World Journal1537-744X2009-01-01982284510.1100/tsw.2009.101Peyronie's Disease: Evolving Surgical Management and the Role of Phosphodiesterase 5 InhibitorsTariq F. Al-Shaiji0Gerald B. Brock1Division of Urology, Department of Surgery, University of Western Ontario, London, ON, CanadaDivision of Urology, Department of Surgery, University of Western Ontario, London, ON, CanadaPeyronie's disease (PD) is a fibrotic disorder of the tunica albuginea of the penis. It is characterized by different degrees of penile curvature and sexual dysfunction. Several medical treatments have been employed to manage the disorder, with variable success rates. Surgical therapy is reserved for patients with severe penile deformity that fails to improve with medical treatment and impedes coital function. The advantages and disadvantages of various surgical approaches have long been debated. Herein, we describe the evolving surgical techniques for PD using knowledge obtained from the contemporary literature. In addition, we discuss the emerging data regarding the role of phosphodiesterase 5 inhibitors in the management of PD.http://dx.doi.org/10.1100/tsw.2009.101 |
| spellingShingle | Tariq F. Al-Shaiji Gerald B. Brock Peyronie's Disease: Evolving Surgical Management and the Role of Phosphodiesterase 5 Inhibitors The Scientific World Journal |
| title | Peyronie's Disease: Evolving Surgical Management and the Role of Phosphodiesterase 5 Inhibitors |
| title_full | Peyronie's Disease: Evolving Surgical Management and the Role of Phosphodiesterase 5 Inhibitors |
| title_fullStr | Peyronie's Disease: Evolving Surgical Management and the Role of Phosphodiesterase 5 Inhibitors |
| title_full_unstemmed | Peyronie's Disease: Evolving Surgical Management and the Role of Phosphodiesterase 5 Inhibitors |
| title_short | Peyronie's Disease: Evolving Surgical Management and the Role of Phosphodiesterase 5 Inhibitors |
| title_sort | peyronie s disease evolving surgical management and the role of phosphodiesterase 5 inhibitors |
| url | http://dx.doi.org/10.1100/tsw.2009.101 |
| work_keys_str_mv | AT tariqfalshaiji peyroniesdiseaseevolvingsurgicalmanagementandtheroleofphosphodiesterase5inhibitors AT geraldbbrock peyroniesdiseaseevolvingsurgicalmanagementandtheroleofphosphodiesterase5inhibitors |