Post-treatment transmissibility of Plasmodium falciparum infections: an observational cohort study

Post-treatment transmissibility of Plasmodium falciparum infections: an observational cohort study

Abstract Background Strengthening malaria control and expediting progress toward elimination requires targeting gametocytes to interrupt transmission. Artemisinin-based combination therapy (ACT) effectively clears Plasmodium falciparum asexual parasites and immature gametocytes but has a limited imp...

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Main Authors: Kassahun Habtamu, Hallelujah Getachew, Ashenafi Abossie, Assalif Demissew, Arega Tsegaye, Teshome Degefa, Daibin Zhong, Xiaoming Wang, Ming-Chieh Lee, Guofa Zhou, Solomon Kibret, Christopher L. King, James W. Kazura, Beyene Petros, Delenasaw Yewhalaw, Guiyun Yan
Format: Article
Language:English
Published: BMC 2025-03-01
Series:Malaria Journal
Subjects:
Artemisinin combination therapy
Single low dose primaquine
Membrane feeding assays
Gametocytes
Plasmodium falciparum
Ethiopia
Online Access:https://doi.org/10.1186/s12936-025-05279-9
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