ECMO Support in Pediatric Populations with the Newborn ECMOLife Centrifugal Pump
<i>Background and Objectives</i>: Pediatric ECMO is a valid support mechanism for refractory cardiac and/or respiratory failure. Magnetic levitation technology applied to the centrifugal pump has reduced the hemolysis caused by this procedure, which can be particularly dangerous, especia...
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MDPI AG
2025-03-01
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| author | Carlo Pace Napoleone Ignazio Condello Maria Teresa Cascarano Enrico Aidala Licia Peruzzi Isabella Molinari Cristina Rivoldini Maria Stella Di Carlo Stefania Iannandrea Enrico Bonaveglio |
| author_facet | Carlo Pace Napoleone Ignazio Condello Maria Teresa Cascarano Enrico Aidala Licia Peruzzi Isabella Molinari Cristina Rivoldini Maria Stella Di Carlo Stefania Iannandrea Enrico Bonaveglio |
| author_sort | Carlo Pace Napoleone |
| collection | DOAJ |
| description | <i>Background and Objectives</i>: Pediatric ECMO is a valid support mechanism for refractory cardiac and/or respiratory failure. Magnetic levitation technology applied to the centrifugal pump has reduced the hemolysis caused by this procedure, which can be particularly dangerous, especially in neonates and small children. ECMOLife, a new magnetic levitation centrifugal pump, has been introduced for these patients. <i>Materials and Methods</i>: Four patients were supported with the ECMOLife System in a newborn setting, with veno-venous application in two cases and veno-arterial in the other two. All parameters related to pump functioning, anticoagulation, hemolysis, and inflammation were recorded for the duration of the support. <i>Results</i>: All patients survived the procedure, in three cases achieving recovery, while one veno-arterial ECMO was switched to VAD, and then the patient underwent heart transplantation. All recorded parameters were compatible with clinical conditions. In particular, free haemoglobin was close to 0 g/L in all recorded samples. The possibility of monitoring pump functioning parameters, venous and arterial O2 saturation, and venous and arterial pressures creates an opportunity to check the adequacy of mechanical support for the clinical condition of the patient. <i>Conclusions</i>: This is the first reported experiment in a newborn setting with ECMOLife mechanical support. At present, ECMOLife represents the only system with a newborn and pediatric pump, allowing for the continuous monitoring of perfusion and hemodynamic parameters, with a large number of facilities for transportation available. |
| format | Article |
| id | doaj-art-a45e9c95da144fba8a9bf6e33386ec29 |
| institution | DOAJ |
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| language | English |
| publishDate | 2025-03-01 |
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| series | Medicina |
| spelling | doaj-art-a45e9c95da144fba8a9bf6e33386ec292025-08-20T02:42:22ZengMDPI AGMedicina1010-660X1648-91442025-03-0161349310.3390/medicina61030493ECMO Support in Pediatric Populations with the Newborn ECMOLife Centrifugal PumpCarlo Pace Napoleone0Ignazio Condello1Maria Teresa Cascarano2Enrico Aidala3Licia Peruzzi4Isabella Molinari5Cristina Rivoldini6Maria Stella Di Carlo7Stefania Iannandrea8Enrico Bonaveglio9Department of Pediatric and Congenital Cardiac Surgery, Regina Margherita Children’s Hospital, 10024 Torino, ItalyDepartment of Cardiac Surgery, Anthea Hospital, GVM Care & Research, Via Camillo Rosalba 35/37, 70124 Bari, ItalyDepartment of Pediatric and Congenital Cardiac Surgery, Regina Margherita Children’s Hospital, 10024 Torino, ItalyDepartment of Pediatric and Congenital Cardiac Surgery, Regina Margherita Children’s Hospital, 10024 Torino, ItalyDepartment of Pediatric and Congenital Cardiac Surgery, Regina Margherita Children’s Hospital, 10024 Torino, ItalyDepartment of Pediatric and Congenital Cardiac Surgery, Regina Margherita Children’s Hospital, 10024 Torino, ItalyDepartment of Pediatric and Congenital Cardiac Surgery, Regina Margherita Children’s Hospital, 10024 Torino, ItalyDepartment of Pediatric and Congenital Cardiac Surgery, Regina Margherita Children’s Hospital, 10024 Torino, ItalyDepartment of Pediatric and Congenital Cardiac Surgery, Regina Margherita Children’s Hospital, 10024 Torino, ItalyDepartment of Pediatric and Congenital Cardiac Surgery, Regina Margherita Children’s Hospital, 10024 Torino, Italy<i>Background and Objectives</i>: Pediatric ECMO is a valid support mechanism for refractory cardiac and/or respiratory failure. Magnetic levitation technology applied to the centrifugal pump has reduced the hemolysis caused by this procedure, which can be particularly dangerous, especially in neonates and small children. ECMOLife, a new magnetic levitation centrifugal pump, has been introduced for these patients. <i>Materials and Methods</i>: Four patients were supported with the ECMOLife System in a newborn setting, with veno-venous application in two cases and veno-arterial in the other two. All parameters related to pump functioning, anticoagulation, hemolysis, and inflammation were recorded for the duration of the support. <i>Results</i>: All patients survived the procedure, in three cases achieving recovery, while one veno-arterial ECMO was switched to VAD, and then the patient underwent heart transplantation. All recorded parameters were compatible with clinical conditions. In particular, free haemoglobin was close to 0 g/L in all recorded samples. The possibility of monitoring pump functioning parameters, venous and arterial O2 saturation, and venous and arterial pressures creates an opportunity to check the adequacy of mechanical support for the clinical condition of the patient. <i>Conclusions</i>: This is the first reported experiment in a newborn setting with ECMOLife mechanical support. At present, ECMOLife represents the only system with a newborn and pediatric pump, allowing for the continuous monitoring of perfusion and hemodynamic parameters, with a large number of facilities for transportation available.https://www.mdpi.com/1648-9144/61/3/493extracorporeal membrane oxygenationmechanical circulatory supportpediatric cardiac failurepediatric respiratory failuremagnetic levitation |
| spellingShingle | Carlo Pace Napoleone Ignazio Condello Maria Teresa Cascarano Enrico Aidala Licia Peruzzi Isabella Molinari Cristina Rivoldini Maria Stella Di Carlo Stefania Iannandrea Enrico Bonaveglio ECMO Support in Pediatric Populations with the Newborn ECMOLife Centrifugal Pump Medicina extracorporeal membrane oxygenation mechanical circulatory support pediatric cardiac failure pediatric respiratory failure magnetic levitation |
| title | ECMO Support in Pediatric Populations with the Newborn ECMOLife Centrifugal Pump |
| title_full | ECMO Support in Pediatric Populations with the Newborn ECMOLife Centrifugal Pump |
| title_fullStr | ECMO Support in Pediatric Populations with the Newborn ECMOLife Centrifugal Pump |
| title_full_unstemmed | ECMO Support in Pediatric Populations with the Newborn ECMOLife Centrifugal Pump |
| title_short | ECMO Support in Pediatric Populations with the Newborn ECMOLife Centrifugal Pump |
| title_sort | ecmo support in pediatric populations with the newborn ecmolife centrifugal pump |
| topic | extracorporeal membrane oxygenation mechanical circulatory support pediatric cardiac failure pediatric respiratory failure magnetic levitation |
| url | https://www.mdpi.com/1648-9144/61/3/493 |
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