General Method for HPLC Purification and Sequencing of Selected dsDNA Gene Fragments from Complex PCRs Generated during Gene Expression Profiling

Gene expression profiling using an AFLP-based technique generates a large number of gene fragments that require identification by sequencing. The DNA fragments vary in length from about 50–500 bp. Ion-pair reversed-phase HPLC can be used to purify selected double-stranded DNA fragments that represen...

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Bibliographic Details
Main Authors: L.Y. Wong, V. Belonogoff, V.L. Boyd, N.M. Hunkapiller, P.M. Casey, S.-N. Liew, K.D. Lazaruk, S. Baumhueter
Format: Article
Language:English
Published: Taylor & Francis Group 2000-04-01
Series:BioTechniques
Online Access:https://www.future-science.com/doi/10.2144/00284rr07
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