Myocardial Restoration: Is It the Cell or the Architecture or Both?
Myocardial infarction is the leading cause of death in developed countries. Cardiac cell therapy has been introduced to clinical trials for more than ten years but its results are still controversial. Tissue engineering has addressed some limitations of cell therapy and appears to be a promising sol...
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| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2012-01-01
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| Series: | Cardiology Research and Practice |
| Online Access: | http://dx.doi.org/10.1155/2012/240497 |
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| _version_ | 1832551329089716224 |
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| author | Duc Thang Vu Theo Kofidis |
| author_facet | Duc Thang Vu Theo Kofidis |
| author_sort | Duc Thang Vu |
| collection | DOAJ |
| description | Myocardial infarction is the leading cause of death in developed countries. Cardiac cell therapy has been introduced to clinical trials for more than ten years but its results are still controversial. Tissue engineering has addressed some limitations of cell therapy and appears to be a promising solution for cardiac regeneration. In this review, we would like to summarize the current understanding about the therapeutic effect of cell therapy and tissue engineering under purview of functional and structural aspects, highlighting actual roles of each therapy towards clinical application. |
| format | Article |
| id | doaj-art-a4510c243bbc41698ee4c568e3183911 |
| institution | Kabale University |
| issn | 2090-8016 2090-0597 |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Cardiology Research and Practice |
| spelling | doaj-art-a4510c243bbc41698ee4c568e31839112025-02-03T06:01:45ZengWileyCardiology Research and Practice2090-80162090-05972012-01-01201210.1155/2012/240497240497Myocardial Restoration: Is It the Cell or the Architecture or Both?Duc Thang Vu0Theo Kofidis1Department of Surgery, Yong Loo Lin School of Medicine, National University of Singapore, 119228, SingaporeDepartment of Surgery, Yong Loo Lin School of Medicine, National University of Singapore, 119228, SingaporeMyocardial infarction is the leading cause of death in developed countries. Cardiac cell therapy has been introduced to clinical trials for more than ten years but its results are still controversial. Tissue engineering has addressed some limitations of cell therapy and appears to be a promising solution for cardiac regeneration. In this review, we would like to summarize the current understanding about the therapeutic effect of cell therapy and tissue engineering under purview of functional and structural aspects, highlighting actual roles of each therapy towards clinical application.http://dx.doi.org/10.1155/2012/240497 |
| spellingShingle | Duc Thang Vu Theo Kofidis Myocardial Restoration: Is It the Cell or the Architecture or Both? Cardiology Research and Practice |
| title | Myocardial Restoration: Is It the Cell or the Architecture or Both? |
| title_full | Myocardial Restoration: Is It the Cell or the Architecture or Both? |
| title_fullStr | Myocardial Restoration: Is It the Cell or the Architecture or Both? |
| title_full_unstemmed | Myocardial Restoration: Is It the Cell or the Architecture or Both? |
| title_short | Myocardial Restoration: Is It the Cell or the Architecture or Both? |
| title_sort | myocardial restoration is it the cell or the architecture or both |
| url | http://dx.doi.org/10.1155/2012/240497 |
| work_keys_str_mv | AT ducthangvu myocardialrestorationisitthecellorthearchitectureorboth AT theokofidis myocardialrestorationisitthecellorthearchitectureorboth |