Surface phenotype and functionality of WNV specific T cells differ with age and disease severity.

Surface phenotype and functionality of WNV specific T cells differ with age and disease severity.

West Nile virus (WNV) infection can result in severe neuroinvasive disease, particularly in persons with advanced age. As rodent models demonstrate that T cells play an important role in limiting WNV infection, and strong T cell responses to WNV have been observed in humans, we postulated that inade...

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Bibliographic Details
Main Authors: Paolo Piazza, Curtis P McMurtrey, Alina Lelic, Robert L Cook, Rachel Hess, Eric Yablonsky, Luann Borowski, Mark B Loeb, Jonathan L Bramson, William H Hildebrand, Charles R Rinaldo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-12-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0015343&type=printable
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