Automated Lobe-Based Airway Labeling

Regional quantitative analysis of airway morphological abnormalities is of great interest in lung disease investigation. Considering that pulmonary lobes are relatively independent functional unit, we develop and test a novel and efficient computerized scheme in this study to automatically and robus...

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Main Authors: Suicheng Gu, Zhimin Wang, Jill M. Siegfried, David Wilson, William L. Bigbee, Jiantao Pu
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:International Journal of Biomedical Imaging
Online Access:http://dx.doi.org/10.1155/2012/382806
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author Suicheng Gu
Zhimin Wang
Jill M. Siegfried
David Wilson
William L. Bigbee
Jiantao Pu
author_facet Suicheng Gu
Zhimin Wang
Jill M. Siegfried
David Wilson
William L. Bigbee
Jiantao Pu
author_sort Suicheng Gu
collection DOAJ
description Regional quantitative analysis of airway morphological abnormalities is of great interest in lung disease investigation. Considering that pulmonary lobes are relatively independent functional unit, we develop and test a novel and efficient computerized scheme in this study to automatically and robustly classify the airways into different categories in terms of pulmonary lobe. Given an airway tree, which could be obtained using any available airway segmentation scheme, the developed approach consists of four basic steps: (1) airway skeletonization or centerline extraction, (2) individual airway branch identification, (3) initial rule-based airway classification/labeling, and (4) self-correction of labeling errors. In order to assess the performance of this approach, we applied it to a dataset consisting of 300 chest CT examinations in a batch manner and asked an image analyst to subjectively examine the labeled results. Our preliminary experiment showed that the labeling accuracy for the right upper lobe, the right middle lobe, the right lower lobe, the left upper lobe, and the left lower lobe is 100%, 99.3%, 99.3%, 100%, and 100%, respectively. Among these, only two cases are incorrectly labeled due to the failures in airway detection. It takes around 2 minutes to label an airway tree using this algorithm.
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spelling doaj-art-a442e2d3fdbf42ff9dd773615c450e202025-08-20T02:20:22ZengWileyInternational Journal of Biomedical Imaging1687-41881687-41962012-01-01201210.1155/2012/382806382806Automated Lobe-Based Airway LabelingSuicheng Gu0Zhimin Wang1Jill M. Siegfried2David Wilson3William L. Bigbee4Jiantao Pu5Department of Radiology, University of Pittsburgh, Pittsburgh, PA 15213, USADepartment of Radiology, University of Pittsburgh, Pittsburgh, PA 15213, USADepartment of of Pharmacology & Chemical Biology, University of Pittsburgh, Pittsburgh, PA 15213, USADepartment of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USADepartment of Epidemiology, University of Pittsburgh, Pittsburgh, PA 15213, USADepartment of Radiology, University of Pittsburgh, Pittsburgh, PA 15213, USARegional quantitative analysis of airway morphological abnormalities is of great interest in lung disease investigation. Considering that pulmonary lobes are relatively independent functional unit, we develop and test a novel and efficient computerized scheme in this study to automatically and robustly classify the airways into different categories in terms of pulmonary lobe. Given an airway tree, which could be obtained using any available airway segmentation scheme, the developed approach consists of four basic steps: (1) airway skeletonization or centerline extraction, (2) individual airway branch identification, (3) initial rule-based airway classification/labeling, and (4) self-correction of labeling errors. In order to assess the performance of this approach, we applied it to a dataset consisting of 300 chest CT examinations in a batch manner and asked an image analyst to subjectively examine the labeled results. Our preliminary experiment showed that the labeling accuracy for the right upper lobe, the right middle lobe, the right lower lobe, the left upper lobe, and the left lower lobe is 100%, 99.3%, 99.3%, 100%, and 100%, respectively. Among these, only two cases are incorrectly labeled due to the failures in airway detection. It takes around 2 minutes to label an airway tree using this algorithm.http://dx.doi.org/10.1155/2012/382806
spellingShingle Suicheng Gu
Zhimin Wang
Jill M. Siegfried
David Wilson
William L. Bigbee
Jiantao Pu
Automated Lobe-Based Airway Labeling
International Journal of Biomedical Imaging
title Automated Lobe-Based Airway Labeling
title_full Automated Lobe-Based Airway Labeling
title_fullStr Automated Lobe-Based Airway Labeling
title_full_unstemmed Automated Lobe-Based Airway Labeling
title_short Automated Lobe-Based Airway Labeling
title_sort automated lobe based airway labeling
url http://dx.doi.org/10.1155/2012/382806
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AT zhiminwang automatedlobebasedairwaylabeling
AT jillmsiegfried automatedlobebasedairwaylabeling
AT davidwilson automatedlobebasedairwaylabeling
AT williamlbigbee automatedlobebasedairwaylabeling
AT jiantaopu automatedlobebasedairwaylabeling