Synthesis of Isoxazolopyridines and Spirooxindoles under Ultrasonic Irradiation and Evaluation of Their Antioxidant Activity

New polycyclic-fused isoxazolo[4,5-e]pyridines and spirooxindoles were obtained via multicomponent reaction of 5-amino-3-methylisoxazole, indan-1,3-dione, and aromatic aldehydes and reaction of 5-amino-3-methylisoxazole, isatin, and β-diketones in the presence of (±)-camphor-10-sulfonic acid as an e...

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Bibliographic Details
Main Author: Emel Pelit
Format: Article
Language:English
Published: Wiley 2017-01-01
Series:Journal of Chemistry
Online Access:http://dx.doi.org/10.1155/2017/9161505
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Summary:New polycyclic-fused isoxazolo[4,5-e]pyridines and spirooxindoles were obtained via multicomponent reaction of 5-amino-3-methylisoxazole, indan-1,3-dione, and aromatic aldehydes and reaction of 5-amino-3-methylisoxazole, isatin, and β-diketones in the presence of (±)-camphor-10-sulfonic acid as an effective and nontoxic organocatalyst under ultrasound-promoted conditions. The antioxidant activity of the novel synthesized compounds was studied.
ISSN:2090-9063
2090-9071