Localized delivery of gel-embedded siRNA nanoparticles for pancreatic cancer treatment: Formulation, biodistribution and bioactivity in mice

Pancreatic cancer (PC) is one of the most lethal malignancies, primarily due to its dense extra-cellular matrix and poor vascularization, which limit effective drug accumulation and therapy. Here, we describe a local siRNA delivery system using thermosensitive hydrogel-embedded na-noparticles (NPs)....

Full description

Saved in:
Bibliographic Details
Main Authors: Majd Agbaria, Doaa Jbara-Agbaria, Gershon Golomb
Format: Article
Language:English
Published: Andover House Inc. 2025-04-01
Series:Precision Nanomedicine
Online Access:https://doi.org/10.33218/001c.136412
Tags: Add Tag
No Tags, Be the first to tag this record!