Localized delivery of gel-embedded siRNA nanoparticles for pancreatic cancer treatment: Formulation, biodistribution and bioactivity in mice
Pancreatic cancer (PC) is one of the most lethal malignancies, primarily due to its dense extra-cellular matrix and poor vascularization, which limit effective drug accumulation and therapy. Here, we describe a local siRNA delivery system using thermosensitive hydrogel-embedded na-noparticles (NPs)....
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| Main Authors: | Majd Agbaria, Doaa Jbara-Agbaria, Gershon Golomb |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Andover House Inc.
2025-04-01
|
| Series: | Precision Nanomedicine |
| Online Access: | https://doi.org/10.33218/001c.136412 |
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