Effect of cisplatin/gold chitosan nanocomposite on oral squamous cell carcinoma and oral epithelial cells

Effect of cisplatin/gold chitosan nanocomposite on oral squamous cell carcinoma and oral epithelial cells

Abstract Background Oral squamous cell carcinoma (OSCC) treatment represents a great challenge, since platinum-based therapeutic agents have deleterious effects on normal cells and tissues. Employing gold nanoparticles (AuNps) as carriers for cisplatin have proved effective in reducing cisplatin dos...

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Bibliographic Details
Main Authors: Basma Abdelrahman Ahmed, Rania Osama M. Mohsen, Marwa Sharaky, Marwa A. Ramadan, Amna H. Faid, Mai Hafez Mohamed
Format: Article
Language:English
Published: BMC 2025-01-01
Series:Cancer Nanotechnology
Subjects:
Oral squamous cell carcinoma
Oral epithelial cells
Cisplatin
Gold nanoparticles
Chitosan
Apoptosis
Online Access:https://doi.org/10.1186/s12645-025-00306-5
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