Bifidobacterium animalis subsp. Lactis BX-BC08 modulates gut microbiota and secretes alpha-Ketoglutaric acid to alleviate MC903-induced atopic dermatitis

Bifidobacterium animalis subsp. Lactis BX-BC08 modulates gut microbiota and secretes alpha-Ketoglutaric acid to alleviate MC903-induced atopic dermatitis

Abstract Objective Bifidobacterium is known to be depleted in patients with atopic dermatitis (AD). This study aims to investigate the potential prophylactic effects of Bifidobacterium animalis subsp. lactis BX-BC08 (B. lactis BX-BC08) in a murine model of AD. Design The immunosuppressive and anti-i...

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Bibliographic Details
Main Authors: Jiamin Zhao, Ling Kui, Jinqun Huang, Jie Deng, Lingjun Liu, Chenwei Zhu, Yanqiang Shi, Chengyi Li, Yue Xiao, Jinshi Yu, Qing Li, Bin Yang, Bingfeng Leng, Hung Chan
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Journal of Translational Medicine
Subjects:
Atopic dermatitis (AD)
alpha-Ketoglutaric acid (AKG)
Probiotics
Bifidobacterium
BX-BC08
Skin-gut axis
Online Access:https://doi.org/10.1186/s12967-025-06769-9
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