Justification of differential approach to management of patient biological waste in nuclear medicine departments

The development of nuclear medicine technologies in the Russian Federation contributes to the implementation of new diagnostic radiopharmaceuticals in practice. Theranostic pairs such as antibodies and peptides labeled diagnostic and therapeutic radionuclides are beginning to be commonly used. The u...

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Main Authors: L. A. Chipiga, A. V. Vodovatov, A. V. Petryakova, I. A. Zvonova, A. A. Stanzhevsky, D. N. Maistrenko, D. A. Vazhenina, D. S. Sysoev
Format: Article
Language:English
Published: Saint-Petersburg Research Institute of Radiation Hygiene after Professor P.V. Ramzaev 2023-01-01
Series:Радиационная гигиена
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Online Access:https://www.radhyg.ru/jour/article/view/909
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author L. A. Chipiga
A. V. Vodovatov
A. V. Petryakova
I. A. Zvonova
A. A. Stanzhevsky
D. N. Maistrenko
D. A. Vazhenina
D. S. Sysoev
author_facet L. A. Chipiga
A. V. Vodovatov
A. V. Petryakova
I. A. Zvonova
A. A. Stanzhevsky
D. N. Maistrenko
D. A. Vazhenina
D. S. Sysoev
author_sort L. A. Chipiga
collection DOAJ
description The development of nuclear medicine technologies in the Russian Federation contributes to the implementation of new diagnostic radiopharmaceuticals in practice. Theranostic pairs such as antibodies and peptides labeled diagnostic and therapeutic radionuclides are beginning to be commonly used. The use of radionuclides with a longer half-life in radionuclide diagnostics causes the updating of the approaches to management of liquid waste generated as a result of the patient’s metabolic activity during the time spent in the radionuclide diagnostics department. Management of liquid radioactive waste in radionuclide diagnostic department is regulated by guidelines MU 2.6.1.1892-04. The guidelines are not the regulatory document. These were developed about 20 years ago, and do not considering features of the modern methods in radionuclide diagnostics, promising radionuclides with half-life of several days, and new criteria for classifying as a radionuclide waste in accordance with Resolution of the Government of the Russian Federation No. 1069. The aim of the study was the assessment of the radionuclide activities excreted from patient after radiopharmaceutical injection in radionuclide diagnostics departments in order to define the waste management pathways. In a result, all diagnostic and therapeutic radiopharmaceuticals were divided into the categories: radiopharmaceuticals with ultrashort-lived radionuclides, which can be discharged into the hospital sewerage without any restrictions; radiopharmaceuticals with 131I, which need the special sewerage; the other radiopharmaceuticals, which need to assess the volume of discharged radionuclide activities during the projection of the nuclear medicine department. The method of assessment of the radionuclide activities entering the hospital sewerage is presented.
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institution Kabale University
issn 1998-426X
language English
publishDate 2023-01-01
publisher Saint-Petersburg Research Institute of Radiation Hygiene after Professor P.V. Ramzaev
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spelling doaj-art-a3f628a041df49feb02830a14c529e832025-08-20T03:43:50ZengSaint-Petersburg Research Institute of Radiation Hygiene after Professor P.V. RamzaevРадиационная гигиена1998-426X2023-01-01154344410.21514/1998-426X-2022-15-4-34-44768Justification of differential approach to management of patient biological waste in nuclear medicine departmentsL. A. Chipiga0A. V. Vodovatov1A. V. Petryakova2I. A. Zvonova3A. A. Stanzhevsky4D. N. Maistrenko5D. A. Vazhenina6D. S. Sysoev7Saint-Petersburg Research Institute of Radiation Hygiene after Professor P.V. Ramzaev, Federal Service for Surveillance on Consumer Rights Protection and Human Well-Being; A. Granov Russian Scientific Center of Radiology and Surgical Technologies of the Ministry of Health of the Russian Federation; Almazov National Medical Research Centre of the Ministry of Health of the Russian FederationSaint-Petersburg Research Institute of Radiation Hygiene after Professor P.V. Ramzaev, Federal Service for Surveillance on Consumer Rights Protection and Human Well-Being; Saint-Petersburg State Pediatric Medical UniversitySaint-Petersburg Research Institute of Radiation Hygiene after Professor P.V. Ramzaev, Federal Service for Surveillance on Consumer Rights Protection and Human Well-Being; The City Hospital No 40 of the Kurortny DistrictSaint-Petersburg Research Institute of Radiation Hygiene after Professor P.V. Ramzaev, Federal Service for Surveillance on Consumer Rights Protection and Human Well-BeingA. Granov Russian Scientific Center of Radiology and Surgical Technologies of the Ministry of Health of the Russian FederationA. Granov Russian Scientific Center of Radiology and Surgical Technologies of the Ministry of Health of the Russian FederationA. Granov Russian Scientific Center of Radiology and Surgical Technologies of the Ministry of Health of the Russian FederationA. Granov Russian Scientific Center of Radiology and Surgical Technologies of the Ministry of Health of the Russian FederationThe development of nuclear medicine technologies in the Russian Federation contributes to the implementation of new diagnostic radiopharmaceuticals in practice. Theranostic pairs such as antibodies and peptides labeled diagnostic and therapeutic radionuclides are beginning to be commonly used. The use of radionuclides with a longer half-life in radionuclide diagnostics causes the updating of the approaches to management of liquid waste generated as a result of the patient’s metabolic activity during the time spent in the radionuclide diagnostics department. Management of liquid radioactive waste in radionuclide diagnostic department is regulated by guidelines MU 2.6.1.1892-04. The guidelines are not the regulatory document. These were developed about 20 years ago, and do not considering features of the modern methods in radionuclide diagnostics, promising radionuclides with half-life of several days, and new criteria for classifying as a radionuclide waste in accordance with Resolution of the Government of the Russian Federation No. 1069. The aim of the study was the assessment of the radionuclide activities excreted from patient after radiopharmaceutical injection in radionuclide diagnostics departments in order to define the waste management pathways. In a result, all diagnostic and therapeutic radiopharmaceuticals were divided into the categories: radiopharmaceuticals with ultrashort-lived radionuclides, which can be discharged into the hospital sewerage without any restrictions; radiopharmaceuticals with 131I, which need the special sewerage; the other radiopharmaceuticals, which need to assess the volume of discharged radionuclide activities during the projection of the nuclear medicine department. The method of assessment of the radionuclide activities entering the hospital sewerage is presented.https://www.radhyg.ru/jour/article/view/909radionuclide diagnosticsradionuclide therapyradiopharmaceuticalliquid radioactive waste
spellingShingle L. A. Chipiga
A. V. Vodovatov
A. V. Petryakova
I. A. Zvonova
A. A. Stanzhevsky
D. N. Maistrenko
D. A. Vazhenina
D. S. Sysoev
Justification of differential approach to management of patient biological waste in nuclear medicine departments
Радиационная гигиена
radionuclide diagnostics
radionuclide therapy
radiopharmaceutical
liquid radioactive waste
title Justification of differential approach to management of patient biological waste in nuclear medicine departments
title_full Justification of differential approach to management of patient biological waste in nuclear medicine departments
title_fullStr Justification of differential approach to management of patient biological waste in nuclear medicine departments
title_full_unstemmed Justification of differential approach to management of patient biological waste in nuclear medicine departments
title_short Justification of differential approach to management of patient biological waste in nuclear medicine departments
title_sort justification of differential approach to management of patient biological waste in nuclear medicine departments
topic radionuclide diagnostics
radionuclide therapy
radiopharmaceutical
liquid radioactive waste
url https://www.radhyg.ru/jour/article/view/909
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AT avpetryakova justificationofdifferentialapproachtomanagementofpatientbiologicalwasteinnuclearmedicinedepartments
AT iazvonova justificationofdifferentialapproachtomanagementofpatientbiologicalwasteinnuclearmedicinedepartments
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