Phytochemistry and Anti-Inflammatory and Antioxidant Activities of <i>Cinnamomum osmophloeum</i> and Its Bioactive Constituents: A Review
<i>Cinnamomum osmophloeum</i>, commonly known as indigenous cinnamon, is a tree species native to Taiwan’s hardwood forests. It has been extensively investigated for its chemical composition and bioactivities. Several reports have shown that <i>C. osmophloeum</i> leaves are r...
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2025-02-01
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| author | Renan Oliveira Silva Damasceno João Lucas Silva Pinheiro Lorena Duarte da Silva Lucas Henrique Marques Rodrigues Jeremias Justo Emídio Tamires Cardoso Lima Damião Pergentino de Sousa |
| author_facet | Renan Oliveira Silva Damasceno João Lucas Silva Pinheiro Lorena Duarte da Silva Lucas Henrique Marques Rodrigues Jeremias Justo Emídio Tamires Cardoso Lima Damião Pergentino de Sousa |
| author_sort | Renan Oliveira Silva Damasceno |
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| description | <i>Cinnamomum osmophloeum</i>, commonly known as indigenous cinnamon, is a tree species native to Taiwan’s hardwood forests. It has been extensively investigated for its chemical composition and bioactivities. Several reports have shown that <i>C. osmophloeum</i> leaves are rich in aromatic oils, which are grouped into various chemotypes based on their major constituents. Components of the volatile oils included phenylpropanoids, monoterpenoids, sesquiterpenoids, phenols, coumarins, and other miscellaneous compounds. In addition, other secondary metabolites previously identified in this species included flavonol glycosides, phenolic acids, lignans, proanthocyanidins, and cyclopropanoids. <i>C. osmophloeum</i> is widely recognized for its medicinal and industrial applications, particularly its essential oils. In general, essential oils exhibit remarkable anti-inflammatory and antioxidant actions, enabling them to modulate key inflammatory mediators and neutralize free radicals. This review explored the phytochemical composition of the essential oils and extracts from <i>C. osmophloeum</i> as well as therapeutic potential of this species, focusing on the action mechanisms and clinical potential. We hope that this review will contribute to a better understanding of the biological effects of this plant and its potential applications in the management of conditions associated with inflammation and oxidative stress. |
| format | Article |
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| language | English |
| publishDate | 2025-02-01 |
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| spelling | doaj-art-a3f145dbff1449f59ee9b57f583ae8a22025-08-20T02:03:27ZengMDPI AGPlants2223-77472025-02-0114456210.3390/plants14040562Phytochemistry and Anti-Inflammatory and Antioxidant Activities of <i>Cinnamomum osmophloeum</i> and Its Bioactive Constituents: A ReviewRenan Oliveira Silva Damasceno0João Lucas Silva Pinheiro1Lorena Duarte da Silva2Lucas Henrique Marques Rodrigues3Jeremias Justo Emídio4Tamires Cardoso Lima5Damião Pergentino de Sousa6Department of Physiology and Pharmacology, Federal University of Pernambuco, Recife 50670-901, Pernambuco, BrazilDepartment of Physiology and Pharmacology, Federal University of Pernambuco, Recife 50670-901, Pernambuco, BrazilDepartment of Physiology and Pharmacology, Federal University of Pernambuco, Recife 50670-901, Pernambuco, BrazilDepartment of Physiology and Pharmacology, Federal University of Pernambuco, Recife 50670-901, Pernambuco, BrazilDepartment of Pharmaceutical Sciences, Federal University of Paraíba, João Pessoa 58051-970, Paraíba, BrazilDepartment of Pharmacy, Federal University of Sergipe, São Cristóvão 49100-000, Sergipe, BrazilDepartment of Pharmaceutical Sciences, Federal University of Paraíba, João Pessoa 58051-970, Paraíba, Brazil<i>Cinnamomum osmophloeum</i>, commonly known as indigenous cinnamon, is a tree species native to Taiwan’s hardwood forests. It has been extensively investigated for its chemical composition and bioactivities. Several reports have shown that <i>C. osmophloeum</i> leaves are rich in aromatic oils, which are grouped into various chemotypes based on their major constituents. Components of the volatile oils included phenylpropanoids, monoterpenoids, sesquiterpenoids, phenols, coumarins, and other miscellaneous compounds. In addition, other secondary metabolites previously identified in this species included flavonol glycosides, phenolic acids, lignans, proanthocyanidins, and cyclopropanoids. <i>C. osmophloeum</i> is widely recognized for its medicinal and industrial applications, particularly its essential oils. In general, essential oils exhibit remarkable anti-inflammatory and antioxidant actions, enabling them to modulate key inflammatory mediators and neutralize free radicals. This review explored the phytochemical composition of the essential oils and extracts from <i>C. osmophloeum</i> as well as therapeutic potential of this species, focusing on the action mechanisms and clinical potential. We hope that this review will contribute to a better understanding of the biological effects of this plant and its potential applications in the management of conditions associated with inflammation and oxidative stress.https://www.mdpi.com/2223-7747/14/4/562<i>Cinnamomum osmophloeum</i>essential oilsphytochemistryanti-inflammatoryantioxidantnatural products |
| spellingShingle | Renan Oliveira Silva Damasceno João Lucas Silva Pinheiro Lorena Duarte da Silva Lucas Henrique Marques Rodrigues Jeremias Justo Emídio Tamires Cardoso Lima Damião Pergentino de Sousa Phytochemistry and Anti-Inflammatory and Antioxidant Activities of <i>Cinnamomum osmophloeum</i> and Its Bioactive Constituents: A Review Plants <i>Cinnamomum osmophloeum</i> essential oils phytochemistry anti-inflammatory antioxidant natural products |
| title | Phytochemistry and Anti-Inflammatory and Antioxidant Activities of <i>Cinnamomum osmophloeum</i> and Its Bioactive Constituents: A Review |
| title_full | Phytochemistry and Anti-Inflammatory and Antioxidant Activities of <i>Cinnamomum osmophloeum</i> and Its Bioactive Constituents: A Review |
| title_fullStr | Phytochemistry and Anti-Inflammatory and Antioxidant Activities of <i>Cinnamomum osmophloeum</i> and Its Bioactive Constituents: A Review |
| title_full_unstemmed | Phytochemistry and Anti-Inflammatory and Antioxidant Activities of <i>Cinnamomum osmophloeum</i> and Its Bioactive Constituents: A Review |
| title_short | Phytochemistry and Anti-Inflammatory and Antioxidant Activities of <i>Cinnamomum osmophloeum</i> and Its Bioactive Constituents: A Review |
| title_sort | phytochemistry and anti inflammatory and antioxidant activities of i cinnamomum osmophloeum i and its bioactive constituents a review |
| topic | <i>Cinnamomum osmophloeum</i> essential oils phytochemistry anti-inflammatory antioxidant natural products |
| url | https://www.mdpi.com/2223-7747/14/4/562 |
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