Silicon-, Silica-, and Silicate-Toothpastes for Remineralization and Repair of Teeth: A Scoping Review
<b>Objective:</b> The purpose of this scoping review was to identify gaps in the literature and summarize findings from studies examining the use of silicon-, silica-, and silicate-based toothpastes for the remineralization and repair of mineralized tooth tissues. <b>Methods</b&...
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MDPI AG
2024-10-01
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| author | Fabio Correia Sampaio Andressa Feitosa Bezerra de Oliveira Nayanna Lana Soares Fernandes Ana Carolina Cheron Gentile Giovanna Bueno Marinho Marcelo José Strazzeri Bönecker Marco Aurelio Benini Paschoal Paulo Henrique Perlatti D’Alpino Fabiano Vieira Vilhena |
| author_facet | Fabio Correia Sampaio Andressa Feitosa Bezerra de Oliveira Nayanna Lana Soares Fernandes Ana Carolina Cheron Gentile Giovanna Bueno Marinho Marcelo José Strazzeri Bönecker Marco Aurelio Benini Paschoal Paulo Henrique Perlatti D’Alpino Fabiano Vieira Vilhena |
| author_sort | Fabio Correia Sampaio |
| collection | DOAJ |
| description | <b>Objective:</b> The purpose of this scoping review was to identify gaps in the literature and summarize findings from studies examining the use of silicon-, silica-, and silicate-based toothpastes for the remineralization and repair of mineralized tooth tissues. <b>Methods</b>: A 10-year literature search was conducted using PubMed and Scopus, adhering to PRISMA 2020 guidelines. A total of 331 studies were initially identified, with 56 full-text review articles. After selecting the manuscripts, 27 studies were qualitatively analyzed by four reviewers, focusing on the results of both in vivo and in vitro methods. <b>Results</b>: The findings suggest that toothpastes containing silicon, silica, and silicate demonstrate promising results for remineralization and enamel repair, with evidence of mineral layer formation and/or deep enamel surface remineralization under various conditions. Additionally, the use of these toothpastes can lead to the obliteration of dentinal tubules within a few days. The results collectively support the efficacy of these toothpastes in enamel repair. Most of the clinical studies focused on dentine hypersensitivity, followed by white spot lesions. <b>Conclusions:</b> Silicon-, silica-, and silicate-based toothpastes (bioactive Si-toothpastes) can be considered effective based mostly on laboratory studies. There remains a need for more in vivo research studies on enamel and dentin mineral repair. Existing studies provide strong evidence that these technologies can reduce dentin hypersensitivity and promote enamel–dentin repair. |
| format | Article |
| id | doaj-art-a3eb46a857f147dc82870a002b13c8a2 |
| institution | DOAJ |
| issn | 2673-6373 |
| language | English |
| publishDate | 2024-10-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Oral |
| spelling | doaj-art-a3eb46a857f147dc82870a002b13c8a22025-08-20T02:57:28ZengMDPI AGOral2673-63732024-10-014446748610.3390/oral4040038Silicon-, Silica-, and Silicate-Toothpastes for Remineralization and Repair of Teeth: A Scoping ReviewFabio Correia Sampaio0Andressa Feitosa Bezerra de Oliveira1Nayanna Lana Soares Fernandes2Ana Carolina Cheron Gentile3Giovanna Bueno Marinho4Marcelo José Strazzeri Bönecker5Marco Aurelio Benini Paschoal6Paulo Henrique Perlatti D’Alpino7Fabiano Vieira Vilhena8Department of Clinical and Community, Health Science Centre, Federal University of Paraíba, Campus I, João Pessoa 58051-900, PB, BrazilDepartment of Morphology, Health Science Centre, Federal University of Paraíba, Campus I, João Pessoa 58051-900, PB, BrazilDepartment of Clinical and Community, Health Science Centre, Federal University of Paraíba, Campus I, João Pessoa 58051-900, PB, BrazilDepartment of Pediatric Dentistry, School of Dentistry, University of São Paulo, São Paulo 58051-900, SP, BrazilDepartment of Pediatric Dentistry, School of Dentistry, University of São Paulo, São Paulo 58051-900, SP, BrazilDepartment of Pediatric Dentistry, School of Dentistry, University of São Paulo, São Paulo 58051-900, SP, BrazilDepartment of Child and Adolescent Oral Health, Dental School, Federal University of Minas Gerais, Belo Horizonte 58051-900, MG, BrazilTriplet Biotechnology Solution, São Paulo 58051-900, SP, BrazilTRIALS—Oral Health & Technologies, Bauru 58051-900, SP, Brazil<b>Objective:</b> The purpose of this scoping review was to identify gaps in the literature and summarize findings from studies examining the use of silicon-, silica-, and silicate-based toothpastes for the remineralization and repair of mineralized tooth tissues. <b>Methods</b>: A 10-year literature search was conducted using PubMed and Scopus, adhering to PRISMA 2020 guidelines. A total of 331 studies were initially identified, with 56 full-text review articles. After selecting the manuscripts, 27 studies were qualitatively analyzed by four reviewers, focusing on the results of both in vivo and in vitro methods. <b>Results</b>: The findings suggest that toothpastes containing silicon, silica, and silicate demonstrate promising results for remineralization and enamel repair, with evidence of mineral layer formation and/or deep enamel surface remineralization under various conditions. Additionally, the use of these toothpastes can lead to the obliteration of dentinal tubules within a few days. The results collectively support the efficacy of these toothpastes in enamel repair. Most of the clinical studies focused on dentine hypersensitivity, followed by white spot lesions. <b>Conclusions:</b> Silicon-, silica-, and silicate-based toothpastes (bioactive Si-toothpastes) can be considered effective based mostly on laboratory studies. There remains a need for more in vivo research studies on enamel and dentin mineral repair. Existing studies provide strong evidence that these technologies can reduce dentin hypersensitivity and promote enamel–dentin repair.https://www.mdpi.com/2673-6373/4/4/38siliconsilicasilicatebioactivetoothpastesdental caries |
| spellingShingle | Fabio Correia Sampaio Andressa Feitosa Bezerra de Oliveira Nayanna Lana Soares Fernandes Ana Carolina Cheron Gentile Giovanna Bueno Marinho Marcelo José Strazzeri Bönecker Marco Aurelio Benini Paschoal Paulo Henrique Perlatti D’Alpino Fabiano Vieira Vilhena Silicon-, Silica-, and Silicate-Toothpastes for Remineralization and Repair of Teeth: A Scoping Review Oral silicon silica silicate bioactive toothpastes dental caries |
| title | Silicon-, Silica-, and Silicate-Toothpastes for Remineralization and Repair of Teeth: A Scoping Review |
| title_full | Silicon-, Silica-, and Silicate-Toothpastes for Remineralization and Repair of Teeth: A Scoping Review |
| title_fullStr | Silicon-, Silica-, and Silicate-Toothpastes for Remineralization and Repair of Teeth: A Scoping Review |
| title_full_unstemmed | Silicon-, Silica-, and Silicate-Toothpastes for Remineralization and Repair of Teeth: A Scoping Review |
| title_short | Silicon-, Silica-, and Silicate-Toothpastes for Remineralization and Repair of Teeth: A Scoping Review |
| title_sort | silicon silica and silicate toothpastes for remineralization and repair of teeth a scoping review |
| topic | silicon silica silicate bioactive toothpastes dental caries |
| url | https://www.mdpi.com/2673-6373/4/4/38 |
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