An herbal medicine prescription (Oreongsan) developed as a new alternative treatment in patients with chronic subdural hematoma: a narrative review
An herbal medicine prescription, Oreongsan (ORS), which is composed of Polyporus, Alismatis Rhizoma, Atractylodis Rhizoma, Poria (Hoelen), and Cinnamomi Cortex Spissus, has been used as treatment in patients with various symptoms such as thirst, diminished urination, edema, hangover, and diarrhea. O...
Saved in:
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2019-03-01
|
| Series: | Integrative Medicine Research |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2213422018302750 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1850153178443546624 |
|---|---|
| author | Seungwon Kwon Chul Jin Ki-Ho Cho |
| author_facet | Seungwon Kwon Chul Jin Ki-Ho Cho |
| author_sort | Seungwon Kwon |
| collection | DOAJ |
| description | An herbal medicine prescription, Oreongsan (ORS), which is composed of Polyporus, Alismatis Rhizoma, Atractylodis Rhizoma, Poria (Hoelen), and Cinnamomi Cortex Spissus, has been used as treatment in patients with various symptoms such as thirst, diminished urination, edema, hangover, and diarrhea. ORS is the representative prescription of the ’inducing diuresis’ (isu) effect, which traditionally means the effect of controlling the water balance. Advancement of modern science has enabled the determination of the action mechanism of herbal medicine complexes. As a result, ORS has been used in the treatment of patients with chronic subdural hematoma (CSDH), representing a novel indication. ORS inhibits the upregulation of aquaporin-4, which is involved in the development of brain edema in the central nervous system. Both aquaporin-1 and aquaporin-4 are expressed in the outer membrane of the CSDH; through its effect as aquaporin-4 inhibitor, ORS prevents the inflow of fluid into the hematoma, thereby preventing the development and recurrence of hematoma. In this study, we reviewed the relationship between the inducing diuresis effect of ORS and aquaporin, conservative treatment approach in patients with CSDH, and the prevention of recurrence in patients undergoing combined burr hole surgery and treatment with ORS. Keywords: Aquaporin-4, Chronic subdural hematoma, Goreisan, Induce diuresis, Oreongsan |
| format | Article |
| id | doaj-art-a3e8feb29fa549fd9e8cc01966dada66 |
| institution | OA Journals |
| issn | 2213-4220 |
| language | English |
| publishDate | 2019-03-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Integrative Medicine Research |
| spelling | doaj-art-a3e8feb29fa549fd9e8cc01966dada662025-08-20T02:25:47ZengElsevierIntegrative Medicine Research2213-42202019-03-0181263010.1016/j.imr.2018.11.003An herbal medicine prescription (Oreongsan) developed as a new alternative treatment in patients with chronic subdural hematoma: a narrative reviewSeungwon Kwon0Chul Jin1Ki-Ho Cho2Department of Cardiology and Neurology, College of Korean Medicine, Kyung Hee University, Seoul, Republic of KoreaDepartment of Cardiology and Neurology, College of Korean Medicine, Kyung Hee University, Seoul, Republic of KoreaCorrespondence author at: Department of Cardiology and Neurology, College of Korean Medicine, Kyung Hee University, 2 KyunHee-daero, Dongdaemun-gu, Seoul 02447, Republic of Korea.; Department of Cardiology and Neurology, College of Korean Medicine, Kyung Hee University, Seoul, Republic of KoreaAn herbal medicine prescription, Oreongsan (ORS), which is composed of Polyporus, Alismatis Rhizoma, Atractylodis Rhizoma, Poria (Hoelen), and Cinnamomi Cortex Spissus, has been used as treatment in patients with various symptoms such as thirst, diminished urination, edema, hangover, and diarrhea. ORS is the representative prescription of the ’inducing diuresis’ (isu) effect, which traditionally means the effect of controlling the water balance. Advancement of modern science has enabled the determination of the action mechanism of herbal medicine complexes. As a result, ORS has been used in the treatment of patients with chronic subdural hematoma (CSDH), representing a novel indication. ORS inhibits the upregulation of aquaporin-4, which is involved in the development of brain edema in the central nervous system. Both aquaporin-1 and aquaporin-4 are expressed in the outer membrane of the CSDH; through its effect as aquaporin-4 inhibitor, ORS prevents the inflow of fluid into the hematoma, thereby preventing the development and recurrence of hematoma. In this study, we reviewed the relationship between the inducing diuresis effect of ORS and aquaporin, conservative treatment approach in patients with CSDH, and the prevention of recurrence in patients undergoing combined burr hole surgery and treatment with ORS. Keywords: Aquaporin-4, Chronic subdural hematoma, Goreisan, Induce diuresis, Oreongsanhttp://www.sciencedirect.com/science/article/pii/S2213422018302750 |
| spellingShingle | Seungwon Kwon Chul Jin Ki-Ho Cho An herbal medicine prescription (Oreongsan) developed as a new alternative treatment in patients with chronic subdural hematoma: a narrative review Integrative Medicine Research |
| title | An herbal medicine prescription (Oreongsan) developed as a new alternative treatment in patients with chronic subdural hematoma: a narrative review |
| title_full | An herbal medicine prescription (Oreongsan) developed as a new alternative treatment in patients with chronic subdural hematoma: a narrative review |
| title_fullStr | An herbal medicine prescription (Oreongsan) developed as a new alternative treatment in patients with chronic subdural hematoma: a narrative review |
| title_full_unstemmed | An herbal medicine prescription (Oreongsan) developed as a new alternative treatment in patients with chronic subdural hematoma: a narrative review |
| title_short | An herbal medicine prescription (Oreongsan) developed as a new alternative treatment in patients with chronic subdural hematoma: a narrative review |
| title_sort | herbal medicine prescription oreongsan developed as a new alternative treatment in patients with chronic subdural hematoma a narrative review |
| url | http://www.sciencedirect.com/science/article/pii/S2213422018302750 |
| work_keys_str_mv | AT seungwonkwon anherbalmedicineprescriptionoreongsandevelopedasanewalternativetreatmentinpatientswithchronicsubduralhematomaanarrativereview AT chuljin anherbalmedicineprescriptionoreongsandevelopedasanewalternativetreatmentinpatientswithchronicsubduralhematomaanarrativereview AT kihocho anherbalmedicineprescriptionoreongsandevelopedasanewalternativetreatmentinpatientswithchronicsubduralhematomaanarrativereview AT seungwonkwon herbalmedicineprescriptionoreongsandevelopedasanewalternativetreatmentinpatientswithchronicsubduralhematomaanarrativereview AT chuljin herbalmedicineprescriptionoreongsandevelopedasanewalternativetreatmentinpatientswithchronicsubduralhematomaanarrativereview AT kihocho herbalmedicineprescriptionoreongsandevelopedasanewalternativetreatmentinpatientswithchronicsubduralhematomaanarrativereview |