Epilepsy in mitochondrial diseases. Clinical lecture
Mitochondrial dysfunction mainly affects organs with high metabolic demand, primarily the brain. Epilepsy is a common phenotypic sign of both syndromic and non-syndromic mitochondrial diseases. Epilepsy in mitochondrial diseases is poorly treatable and is often an unfavorable prognostic sign. Patien...
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| Format: | Article |
| Language: | Russian |
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ABV-press
2023-05-01
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| Series: | Русский журнал детской неврологии |
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| Online Access: | https://rjdn.abvpress.ru/jour/article/view/425 |
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| author | A. S. Kotov K. V. Firsov |
| author_facet | A. S. Kotov K. V. Firsov |
| author_sort | A. S. Kotov |
| collection | DOAJ |
| description | Mitochondrial dysfunction mainly affects organs with high metabolic demand, primarily the brain. Epilepsy is a common phenotypic sign of both syndromic and non-syndromic mitochondrial diseases. Epilepsy in mitochondrial diseases is poorly treatable and is often an unfavorable prognostic sign. Patients with mitochondrial epilepsy are prescribed various anti-seizure medications. Mitochondriotoxic drugs should be avoided. Descriptions of MELAS-syndrome, MERRF-syndrome, Leigh-syndrome, NARP-syndrome are given. |
| format | Article |
| id | doaj-art-a3e68cc9994a4fb88666c4940ec1cf71 |
| institution | DOAJ |
| issn | 2073-8803 2412-9178 |
| language | Russian |
| publishDate | 2023-05-01 |
| publisher | ABV-press |
| record_format | Article |
| series | Русский журнал детской неврологии |
| spelling | doaj-art-a3e68cc9994a4fb88666c4940ec1cf712025-08-20T02:56:07ZrusABV-pressРусский журнал детской неврологии2073-88032412-91782023-05-01174637010.17650/2073-8803-2022-17-4-63-70286Epilepsy in mitochondrial diseases. Clinical lectureA. S. Kotov0K. V. Firsov1M. F. Vladimirskiy Moscow Regional Research Clinical InstituteM. F. Vladimirskiy Moscow Regional Research Clinical InstituteMitochondrial dysfunction mainly affects organs with high metabolic demand, primarily the brain. Epilepsy is a common phenotypic sign of both syndromic and non-syndromic mitochondrial diseases. Epilepsy in mitochondrial diseases is poorly treatable and is often an unfavorable prognostic sign. Patients with mitochondrial epilepsy are prescribed various anti-seizure medications. Mitochondriotoxic drugs should be avoided. Descriptions of MELAS-syndrome, MERRF-syndrome, Leigh-syndrome, NARP-syndrome are given.https://rjdn.abvpress.ru/jour/article/view/425epilepsyseizuremitochondriamelasmerrfleighnarp |
| spellingShingle | A. S. Kotov K. V. Firsov Epilepsy in mitochondrial diseases. Clinical lecture Русский журнал детской неврологии epilepsy seizure mitochondria melas merrf leigh narp |
| title | Epilepsy in mitochondrial diseases. Clinical lecture |
| title_full | Epilepsy in mitochondrial diseases. Clinical lecture |
| title_fullStr | Epilepsy in mitochondrial diseases. Clinical lecture |
| title_full_unstemmed | Epilepsy in mitochondrial diseases. Clinical lecture |
| title_short | Epilepsy in mitochondrial diseases. Clinical lecture |
| title_sort | epilepsy in mitochondrial diseases clinical lecture |
| topic | epilepsy seizure mitochondria melas merrf leigh narp |
| url | https://rjdn.abvpress.ru/jour/article/view/425 |
| work_keys_str_mv | AT askotov epilepsyinmitochondrialdiseasesclinicallecture AT kvfirsov epilepsyinmitochondrialdiseasesclinicallecture |