The role of sphingolipid rheostat in the adult-type diffuse glioma pathogenesis

The role of sphingolipid rheostat in the adult-type diffuse glioma pathogenesis

Gliomas are highly aggressive primary brain tumors, with glioblastoma multiforme being the most severe and the most common one. Aberrations in sphingolipid metabolism are a hallmark of glioma cells. The sphingolipid rheostat represents the balance between the pro-apoptotic ceramide and pro-survival...

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Bibliographic Details
Main Authors:	Ivana Karmelić, Mia Jurilj Sajko, Tomislav Sajko, Krešimir Rotim, Dragana Fabris
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2024-12-01
Series:	Frontiers in Cell and Developmental Biology
Subjects:	diffuse glioma glioblastoma sphingosine-1-phosphate ceramides sphingolipid rheostat
Online Access:	https://www.frontiersin.org/articles/10.3389/fcell.2024.1466141/full
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