Chromosome-level haplotype-resolved genome assembly of bread wheat’s wild relative Aegilops mutica

Abstract Bread wheat (Triticum aestivum) is a vital staple crop, with an urgent need for increased production to help feed the world’s growing population. Aegilops mutica (2n = 2x = 14; T genome) is a diploid wild relative of wheat carrying valuable agronomic traits resulting in its extensive exploi...

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Main Authors: Surbhi Grewal, Cai-yun Yang, Ksenia Krasheninnikova, Joanna Collins, Jonathan M. D. Wood, Stephen Ashling, Duncan Scholefield, Gemy G. Kaithakottil, David Swarbreck, Eric Yao, Taner Z. Sen, Ian P. King, Julie King
Format: Article
Language:English
Published: Nature Portfolio 2025-03-01
Series:Scientific Data
Online Access:https://doi.org/10.1038/s41597-025-04737-y
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author Surbhi Grewal
Cai-yun Yang
Ksenia Krasheninnikova
Joanna Collins
Jonathan M. D. Wood
Stephen Ashling
Duncan Scholefield
Gemy G. Kaithakottil
David Swarbreck
Eric Yao
Taner Z. Sen
Ian P. King
Julie King
author_facet Surbhi Grewal
Cai-yun Yang
Ksenia Krasheninnikova
Joanna Collins
Jonathan M. D. Wood
Stephen Ashling
Duncan Scholefield
Gemy G. Kaithakottil
David Swarbreck
Eric Yao
Taner Z. Sen
Ian P. King
Julie King
author_sort Surbhi Grewal
collection DOAJ
description Abstract Bread wheat (Triticum aestivum) is a vital staple crop, with an urgent need for increased production to help feed the world’s growing population. Aegilops mutica (2n = 2x = 14; T genome) is a diploid wild relative of wheat carrying valuable agronomic traits resulting in its extensive exploitation for wheat improvement. This paper reports a chromosome-scale, haplotype-resolved genome assembly of Ae. mutica using HiFi reads and Omni-C data. The final lengths for the curated genomes were ~4.65 Gb (haplotype 1) and 4.56 Gb (haplotype 2), featuring a contig N50 of ~4.35 Mb and ~4.60 Mb, respectively. Genome annotation predicted 96,723 gene models and repeats. In summary, the genome assembly of Ae. mutica provides a valuable resource for the wheat breeding community, facilitating faster and more efficient pre-breeding of wheat to enhance food security.
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publishDate 2025-03-01
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spelling doaj-art-a3dfb05c867f4209983c58c4fce29de52025-08-20T02:56:10ZengNature PortfolioScientific Data2052-44632025-03-0112111210.1038/s41597-025-04737-yChromosome-level haplotype-resolved genome assembly of bread wheat’s wild relative Aegilops muticaSurbhi Grewal0Cai-yun Yang1Ksenia Krasheninnikova2Joanna Collins3Jonathan M. D. Wood4Stephen Ashling5Duncan Scholefield6Gemy G. Kaithakottil7David Swarbreck8Eric Yao9Taner Z. Sen10Ian P. King11Julie King12Wheat Research Centre, School of Biosciences, University of NottinghamWheat Research Centre, School of Biosciences, University of NottinghamWellcome Sanger Institute, Wellcome Trust Genome CampusWellcome Sanger Institute, Wellcome Trust Genome CampusWellcome Sanger Institute, Wellcome Trust Genome CampusWheat Research Centre, School of Biosciences, University of NottinghamWheat Research Centre, School of Biosciences, University of NottinghamEarlham Institute, Norwich Research ParkEarlham Institute, Norwich Research ParkUnited States Department of Agriculture—Agricultural Research Service, Western Regional Research Center, Crop Improvement and Genetics Research UnitUnited States Department of Agriculture—Agricultural Research Service, Western Regional Research Center, Crop Improvement and Genetics Research UnitWheat Research Centre, School of Biosciences, University of NottinghamWheat Research Centre, School of Biosciences, University of NottinghamAbstract Bread wheat (Triticum aestivum) is a vital staple crop, with an urgent need for increased production to help feed the world’s growing population. Aegilops mutica (2n = 2x = 14; T genome) is a diploid wild relative of wheat carrying valuable agronomic traits resulting in its extensive exploitation for wheat improvement. This paper reports a chromosome-scale, haplotype-resolved genome assembly of Ae. mutica using HiFi reads and Omni-C data. The final lengths for the curated genomes were ~4.65 Gb (haplotype 1) and 4.56 Gb (haplotype 2), featuring a contig N50 of ~4.35 Mb and ~4.60 Mb, respectively. Genome annotation predicted 96,723 gene models and repeats. In summary, the genome assembly of Ae. mutica provides a valuable resource for the wheat breeding community, facilitating faster and more efficient pre-breeding of wheat to enhance food security.https://doi.org/10.1038/s41597-025-04737-y
spellingShingle Surbhi Grewal
Cai-yun Yang
Ksenia Krasheninnikova
Joanna Collins
Jonathan M. D. Wood
Stephen Ashling
Duncan Scholefield
Gemy G. Kaithakottil
David Swarbreck
Eric Yao
Taner Z. Sen
Ian P. King
Julie King
Chromosome-level haplotype-resolved genome assembly of bread wheat’s wild relative Aegilops mutica
Scientific Data
title Chromosome-level haplotype-resolved genome assembly of bread wheat’s wild relative Aegilops mutica
title_full Chromosome-level haplotype-resolved genome assembly of bread wheat’s wild relative Aegilops mutica
title_fullStr Chromosome-level haplotype-resolved genome assembly of bread wheat’s wild relative Aegilops mutica
title_full_unstemmed Chromosome-level haplotype-resolved genome assembly of bread wheat’s wild relative Aegilops mutica
title_short Chromosome-level haplotype-resolved genome assembly of bread wheat’s wild relative Aegilops mutica
title_sort chromosome level haplotype resolved genome assembly of bread wheat s wild relative aegilops mutica
url https://doi.org/10.1038/s41597-025-04737-y
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