TARGETING PRC2 ENHANCES THE ANTITUMOR CYTOTOXIC CAPACITY OF ANTI-CD19 CAR-T CELLS AGAINST HEMATOLOGICAL MALIGNANCIES

Chimeric Antigen Receptor (CAR) T cell therapy was adopted as a clinical modality for patients with relapsed/refractory hematological malignancies. Despite the clinical efficacy of CAR-T cell therapy, a considerable fraction of patients still relapses during the first months following CAR-T cell inf...

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Bibliographic Details
Main Authors: MLR Carvalho, CO Andrade, MP Cabral-Piccin, GS Kinker, GAF Vitiello, L Abdo, RAG Cambui, MH Bonamino, TS Medina
Format: Article
Language:English
Published: Elsevier 2024-10-01
Series:Hematology, Transfusion and Cell Therapy
Online Access:http://www.sciencedirect.com/science/article/pii/S2531137924019989
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