Identification of causative agents of infective endocarditis by metagenomic next-generation sequencing of resected valves

Identification of causative agents of infective endocarditis by metagenomic next-generation sequencing of resected valves

BackgroundInfective endocarditis (IE) is a rare and life-threatening condition with considerable mortality rates. Diagnosis is often complicated by negative blood culture results, limiting the accurate identification of causative pathogens. This study aimed to evaluate the effectiveness of metagenom...

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Bibliographic Details
Main Authors: Vladimir Lazarevic, Nadia Gaïa, Truong-Thanh Pham, Mikaël de Lorenzi-Tognon, Myriam Girard, Florian Mauffrey, Yannick Charretier, Gesuele Renzi, Christoph Huber, Jacques Schrenzel
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-03-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
cardiac surgery
clinical metagenomics
heart valve
microbiome
next-generation sequencing
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2025.1532257/full
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