Association between alcohol drinking frequency and depression among adults in the United States: a cross-sectional study

Abstract Background Depression is a major contributor to the global burden of diseases, and alcohol intake is often considered to be associated with depression. However, the relationship between alcohol drinking frequency and depression remains unclear. This study aims to explore the association bet...

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Main Authors: Peng Qi, Mengjie Huang, Haiyan Zhu
Format: Article
Language:English
Published: BMC 2024-11-01
Series:BMC Psychiatry
Subjects:
Online Access:https://doi.org/10.1186/s12888-024-06296-9
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author Peng Qi
Mengjie Huang
Haiyan Zhu
author_facet Peng Qi
Mengjie Huang
Haiyan Zhu
author_sort Peng Qi
collection DOAJ
description Abstract Background Depression is a major contributor to the global burden of diseases, and alcohol intake is often considered to be associated with depression. However, the relationship between alcohol drinking frequency and depression remains unclear. This study aims to explore the association between alcohol drinking frequency and depression. Methods This study collected NHANES data from 2009 to 2016, involving 17,466 participants. Depression was diagnosed based on the Patient Health Questionnaire-9 (PHQ-9), and alcohol drinking frequency was collected through questionnaire surveys. Multifactorial logistic regression models, subgroup analysis, smooth curve fitting, and threshold effect analysis were used to investigate the relationship between alcohol drinking frequency and depression. Results We divided the alcohol drinking frequency into five groups on average. After adjusting for all covariates, the Q3 group had the lowest odds of depression (OR = 0.68; 95% CI: 0.56 ~ 0.82; p < 0.05). Through smooth curve fitting, we found an “M-shaped” relationship between alcohol drinking frequency and depression. Further threshold effect analysis revealed that the most significant inflection points were 80 and 150. Conclusion In this cross-sectional study of American adults, we found an “M-shaped” relationship between alcohol drinking frequency and depression, which may partially explain the different effects of moderate alcohol consumption on depression.
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spelling doaj-art-a3bb38ec40cb469aaf8dd8154af55ae72024-11-24T12:37:58ZengBMCBMC Psychiatry1471-244X2024-11-0124111010.1186/s12888-024-06296-9Association between alcohol drinking frequency and depression among adults in the United States: a cross-sectional studyPeng Qi0Mengjie Huang1Haiyan Zhu2Department of Emergency, First Medical Center of Chinese PLA General HospitalDepartment of Nephrology, First Medical Center of Chinese PLA General HospitalDepartment of Emergency, First Medical Center of Chinese PLA General HospitalAbstract Background Depression is a major contributor to the global burden of diseases, and alcohol intake is often considered to be associated with depression. However, the relationship between alcohol drinking frequency and depression remains unclear. This study aims to explore the association between alcohol drinking frequency and depression. Methods This study collected NHANES data from 2009 to 2016, involving 17,466 participants. Depression was diagnosed based on the Patient Health Questionnaire-9 (PHQ-9), and alcohol drinking frequency was collected through questionnaire surveys. Multifactorial logistic regression models, subgroup analysis, smooth curve fitting, and threshold effect analysis were used to investigate the relationship between alcohol drinking frequency and depression. Results We divided the alcohol drinking frequency into five groups on average. After adjusting for all covariates, the Q3 group had the lowest odds of depression (OR = 0.68; 95% CI: 0.56 ~ 0.82; p < 0.05). Through smooth curve fitting, we found an “M-shaped” relationship between alcohol drinking frequency and depression. Further threshold effect analysis revealed that the most significant inflection points were 80 and 150. Conclusion In this cross-sectional study of American adults, we found an “M-shaped” relationship between alcohol drinking frequency and depression, which may partially explain the different effects of moderate alcohol consumption on depression.https://doi.org/10.1186/s12888-024-06296-9Cross-sectional studyAlcohol consumptionDepressionNHANES
spellingShingle Peng Qi
Mengjie Huang
Haiyan Zhu
Association between alcohol drinking frequency and depression among adults in the United States: a cross-sectional study
BMC Psychiatry
Cross-sectional study
Alcohol consumption
Depression
NHANES
title Association between alcohol drinking frequency and depression among adults in the United States: a cross-sectional study
title_full Association between alcohol drinking frequency and depression among adults in the United States: a cross-sectional study
title_fullStr Association between alcohol drinking frequency and depression among adults in the United States: a cross-sectional study
title_full_unstemmed Association between alcohol drinking frequency and depression among adults in the United States: a cross-sectional study
title_short Association between alcohol drinking frequency and depression among adults in the United States: a cross-sectional study
title_sort association between alcohol drinking frequency and depression among adults in the united states a cross sectional study
topic Cross-sectional study
Alcohol consumption
Depression
NHANES
url https://doi.org/10.1186/s12888-024-06296-9
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AT mengjiehuang associationbetweenalcoholdrinkingfrequencyanddepressionamongadultsintheunitedstatesacrosssectionalstudy
AT haiyanzhu associationbetweenalcoholdrinkingfrequencyanddepressionamongadultsintheunitedstatesacrosssectionalstudy