Risk factors of self-interruption of medications for mental disorders in pregnancy

The current study examined factors associated with the increased risk of self-interruption of medications for mental disorders in pregnancy. We reviewed the obstetric records of all singleton deliveries beyond 22 weeks of gestation at Japanese Red Cross Katsushika Maternity Hospital form January 201...

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Main Authors: J. Ogawa, S. Suzuki
Format: Article
Language:English
Published: IMR Press 2020-08-01
Series:Clinical and Experimental Obstetrics & Gynecology
Subjects:
Online Access:https://www.imrpress.com/journal/CEOG/47/4/10.31083/j.ceog.2020.04.5303
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author J. Ogawa
S. Suzuki
author_facet J. Ogawa
S. Suzuki
author_sort J. Ogawa
collection DOAJ
description The current study examined factors associated with the increased risk of self-interruption of medications for mental disorders in pregnancy. We reviewed the obstetric records of all singleton deliveries beyond 22 weeks of gestation at Japanese Red Cross Katsushika Maternity Hospital form January 2014 through July 2018. We examined the clinical and social characteristics and obstetric outcomes in women with self-interruption of medications for mental disorders in pregnancy in comparison with those in women who continued the medications throughout the pregnancy. There were 177 women who were diagnosed with mental disorders requiring medications before pregnancy by Japanese psychiatric specialists. Of these, 46 (26%) self-interruptedi their medications during the first trimester of their pregnancies. The rates of partners with mental disorders (odds ratio: 4.39, p = 0.01) and presence of social support (odds ratio: 2.50, p = 0.02) in women showing self-interruption of their medications were significantly higher than those in women continuing the medications. In the presence of both factors of a partner's mental disorders and social support, the odds ratio for self-interruption of medications increased to 15.9 (95% confidence interval 2.4-100, p < 0.01). We believe that it may be the possible to identify women at high risk of self-interruption of medications during pregnancy. In women requiring perinatal mental health care, mental health support of their partners may also be needed.
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spelling doaj-art-a3b90fcce7f4416bb6203ea7f530a51e2025-08-20T01:59:43ZengIMR PressClinical and Experimental Obstetrics & Gynecology0390-66632020-08-0147457657810.31083/j.ceog.2020.04.5303S0390-6663(20)00315-2Risk factors of self-interruption of medications for mental disorders in pregnancyJ. Ogawa0S. Suzuki1Department of Obstetrics and Gynecology, Japanese Red Cross Katsushika Maternity Hospital, Tokyo, JapanDepartment of Obstetrics and Gynecology, Japanese Red Cross Katsushika Maternity Hospital, Tokyo, JapanThe current study examined factors associated with the increased risk of self-interruption of medications for mental disorders in pregnancy. We reviewed the obstetric records of all singleton deliveries beyond 22 weeks of gestation at Japanese Red Cross Katsushika Maternity Hospital form January 2014 through July 2018. We examined the clinical and social characteristics and obstetric outcomes in women with self-interruption of medications for mental disorders in pregnancy in comparison with those in women who continued the medications throughout the pregnancy. There were 177 women who were diagnosed with mental disorders requiring medications before pregnancy by Japanese psychiatric specialists. Of these, 46 (26%) self-interruptedi their medications during the first trimester of their pregnancies. The rates of partners with mental disorders (odds ratio: 4.39, p = 0.01) and presence of social support (odds ratio: 2.50, p = 0.02) in women showing self-interruption of their medications were significantly higher than those in women continuing the medications. In the presence of both factors of a partner's mental disorders and social support, the odds ratio for self-interruption of medications increased to 15.9 (95% confidence interval 2.4-100, p < 0.01). We believe that it may be the possible to identify women at high risk of self-interruption of medications during pregnancy. In women requiring perinatal mental health care, mental health support of their partners may also be needed.https://www.imrpress.com/journal/CEOG/47/4/10.31083/j.ceog.2020.04.5303risk factorsself-interruption of medicationsmental disorderspregnancy
spellingShingle J. Ogawa
S. Suzuki
Risk factors of self-interruption of medications for mental disorders in pregnancy
Clinical and Experimental Obstetrics & Gynecology
risk factors
self-interruption of medications
mental disorders
pregnancy
title Risk factors of self-interruption of medications for mental disorders in pregnancy
title_full Risk factors of self-interruption of medications for mental disorders in pregnancy
title_fullStr Risk factors of self-interruption of medications for mental disorders in pregnancy
title_full_unstemmed Risk factors of self-interruption of medications for mental disorders in pregnancy
title_short Risk factors of self-interruption of medications for mental disorders in pregnancy
title_sort risk factors of self interruption of medications for mental disorders in pregnancy
topic risk factors
self-interruption of medications
mental disorders
pregnancy
url https://www.imrpress.com/journal/CEOG/47/4/10.31083/j.ceog.2020.04.5303
work_keys_str_mv AT jogawa riskfactorsofselfinterruptionofmedicationsformentaldisordersinpregnancy
AT ssuzuki riskfactorsofselfinterruptionofmedicationsformentaldisordersinpregnancy