Morphology of exorbital lacrimal glands of not purebred white rats at high-intensity light influence
Purpose: this study morphological changes the exorbital lacrimal glands at experimental impact on an organ of vision of high-intensity light.Material and methods. White not purebred rats males (n = 40) were subjected to continuous influence of light intensity by 3500 lx within 1, 7, 14 and 30 days,...
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Siberian State Medical University (Tomsk)
2017-01-01
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| Series: | Бюллетень сибирской медицины |
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| Online Access: | https://bulletin.ssmu.ru/jour/article/view/738 |
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| author | L. R. Mustafina A. D. Zhuravleva S. V. Logvinov M. R. Karpova T. V. Lasukova G. A. Sukhanova N. N. Ilinskich |
| author_facet | L. R. Mustafina A. D. Zhuravleva S. V. Logvinov M. R. Karpova T. V. Lasukova G. A. Sukhanova N. N. Ilinskich |
| author_sort | L. R. Mustafina |
| collection | DOAJ |
| description | Purpose: this study morphological changes the exorbital lacrimal glands at experimental impact on an organ of vision of high-intensity light.Material and methods. White not purebred rats males (n = 40) were subjected to continuous influence of light intensity by 3500 lx within 1, 7, 14 and 30 days, the control group (n = 10) contained in conditions of natural lighting (20 lx). Exorbital lacrimal glands fixed in formalin, embedded in paraffin wax, stained hematoxylin-eosine. By means of an oculary insert of Avtandilov counted specific volumes of output channels, an epithelium, stroma and vessels of exorbital lacrimal glands, defined an epitelio/stroma ratio. The analysis of data was carried out by methods of descriptive statistics with calculation of a median (Ме) and interquartile range (Q1 –Q3). For an assessment of distinctions used nonparametric criterion of Mann – Whitney.Results. In 1 days in response to high-intensity light influence there is a reflex strengthening of synthetic function of exorbital lacrimal glands. For the 7th days the first signs of violation of functioning with development of hydropic dystrophy in the lacrimacytes appear. By 14th days fibrous changes develop, in a glandular parenchyma harderization sites appear. For the 30th days the nuclear pycnosis of separate lacrimacit, accumulation of a lipofuscin in cytoplasm is observed.Conclusion. The obtained data allow to estimate in dynamics compensatory and adaptive reactions of lacrimal gland in response to high-intensity light influence from the moment of the beginning of their development before emergence of the first signs of a decompensation. |
| format | Article |
| id | doaj-art-a3b66899374b47268693ca3c3f3f43df |
| institution | Kabale University |
| issn | 1682-0363 1819-3684 |
| language | English |
| publishDate | 2017-01-01 |
| publisher | Siberian State Medical University (Tomsk) |
| record_format | Article |
| series | Бюллетень сибирской медицины |
| spelling | doaj-art-a3b66899374b47268693ca3c3f3f43df2025-08-20T04:00:12ZengSiberian State Medical University (Tomsk)Бюллетень сибирской медицины1682-03631819-36842017-01-011559710410.20538/1682-0363-2016-5-97-104605Morphology of exorbital lacrimal glands of not purebred white rats at high-intensity light influenceL. R. Mustafina0A. D. Zhuravleva1S. V. Logvinov2M. R. Karpova3T. V. Lasukova4G. A. Sukhanova5N. N. Ilinskich6Siberian State Medical UniversitySiberian State Medical UniversitySiberian State Medical UniversitySiberian State Medical UniversityTomsk State Pedagogical UniversitySiberian State Medical UniversitySiberian State Medical UniversityPurpose: this study morphological changes the exorbital lacrimal glands at experimental impact on an organ of vision of high-intensity light.Material and methods. White not purebred rats males (n = 40) were subjected to continuous influence of light intensity by 3500 lx within 1, 7, 14 and 30 days, the control group (n = 10) contained in conditions of natural lighting (20 lx). Exorbital lacrimal glands fixed in formalin, embedded in paraffin wax, stained hematoxylin-eosine. By means of an oculary insert of Avtandilov counted specific volumes of output channels, an epithelium, stroma and vessels of exorbital lacrimal glands, defined an epitelio/stroma ratio. The analysis of data was carried out by methods of descriptive statistics with calculation of a median (Ме) and interquartile range (Q1 –Q3). For an assessment of distinctions used nonparametric criterion of Mann – Whitney.Results. In 1 days in response to high-intensity light influence there is a reflex strengthening of synthetic function of exorbital lacrimal glands. For the 7th days the first signs of violation of functioning with development of hydropic dystrophy in the lacrimacytes appear. By 14th days fibrous changes develop, in a glandular parenchyma harderization sites appear. For the 30th days the nuclear pycnosis of separate lacrimacit, accumulation of a lipofuscin in cytoplasm is observed.Conclusion. The obtained data allow to estimate in dynamics compensatory and adaptive reactions of lacrimal gland in response to high-intensity light influence from the moment of the beginning of their development before emergence of the first signs of a decompensation.https://bulletin.ssmu.ru/jour/article/view/738exorbital lacrimal glandshigh-intensity light influence |
| spellingShingle | L. R. Mustafina A. D. Zhuravleva S. V. Logvinov M. R. Karpova T. V. Lasukova G. A. Sukhanova N. N. Ilinskich Morphology of exorbital lacrimal glands of not purebred white rats at high-intensity light influence Бюллетень сибирской медицины exorbital lacrimal glands high-intensity light influence |
| title | Morphology of exorbital lacrimal glands of not purebred white rats at high-intensity light influence |
| title_full | Morphology of exorbital lacrimal glands of not purebred white rats at high-intensity light influence |
| title_fullStr | Morphology of exorbital lacrimal glands of not purebred white rats at high-intensity light influence |
| title_full_unstemmed | Morphology of exorbital lacrimal glands of not purebred white rats at high-intensity light influence |
| title_short | Morphology of exorbital lacrimal glands of not purebred white rats at high-intensity light influence |
| title_sort | morphology of exorbital lacrimal glands of not purebred white rats at high intensity light influence |
| topic | exorbital lacrimal glands high-intensity light influence |
| url | https://bulletin.ssmu.ru/jour/article/view/738 |
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