RNA-Seq profiling reveals novel hepatic gene expression pattern in aflatoxin B1 treated rats.
Deep sequencing was used to investigate the subchronic effects of 1 ppm aflatoxin B1 (AFB1), a potent hepatocarcinogen, on the male rat liver transcriptome prior to onset of histopathological lesions or tumors. We hypothesized RNA-Seq would reveal more differentially expressed genes (DEG) than micro...
Saved in:
| Main Authors: | B Alex Merrick, Dhiral P Phadke, Scott S Auerbach, Deepak Mav, Suzy M Stiegelmeyer, Ruchir R Shah, Raymond R Tice |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2013-01-01
|
| Series: | PLoS ONE |
| Online Access: | https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0061768&type=printable |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
The transcription factors Snail and Slug activate the transforming growth factor-beta signaling pathway in breast cancer.
by: Archana Dhasarathy, et al.
Published: (2011-01-01) -
Identification and evaluation of biomarkers for diagnosis of chronic hepatitis B using RNA-seq
by: Hong Hong, et al.
Published: (2025-08-01) -
Differential Hepatic Expression of miRNA in Response to Aflatoxin B1 Challenge in Domestic and Wild Turkeys
by: Kade Jorud, et al.
Published: (2024-10-01) -
Integrating gonadal RNA-seq and small RNA-seq to analyze mRNA and miRNA changes in medaka sex differentiation
by: Xing Lin, et al.
Published: (2025-05-01) -
Optimized methods for scRNA-seq and snRNA-seq of skeletal muscle stored in nucleic acid stabilizing preservative
by: Elisabeth F. Heuston, et al.
Published: (2025-01-01)