Efficacy and safety of selective laser trabeculoplasty for uveitic glaucoma
Abstract To determine the efficacy and safety of selective laser trabeculoplasty (SLT) in patients with uveitic glaucoma, we retrospectively evaluated 17 eyes from 13 consecutive uveitic glaucoma cases who were treated with SLT due to inadequate interocular pressure (IOP) control despite glaucoma me...
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Nature Portfolio
2025-02-01
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| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-025-88354-0 |
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| author | Minako Suzuki Masaki Takeuchi Akira Meguro Jutaro Nakamura Mamoru Tateishi Miki Fukuda Akihiro Kamata Yuki Mizuki Kayoko Yamada Etsuko Shibuya Norihiro Yamada Mami Ishihara Nobuhisa Mizuki |
| author_facet | Minako Suzuki Masaki Takeuchi Akira Meguro Jutaro Nakamura Mamoru Tateishi Miki Fukuda Akihiro Kamata Yuki Mizuki Kayoko Yamada Etsuko Shibuya Norihiro Yamada Mami Ishihara Nobuhisa Mizuki |
| author_sort | Minako Suzuki |
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| description | Abstract To determine the efficacy and safety of selective laser trabeculoplasty (SLT) in patients with uveitic glaucoma, we retrospectively evaluated 17 eyes from 13 consecutive uveitic glaucoma cases who were treated with SLT due to inadequate interocular pressure (IOP) control despite glaucoma medical therapy. The mean IOP was significantly decreased from 28.4 ± 6.50 mmHg to 17.3 ± 9.4 mmHg at baseline, and 6 months after SLT, respectively (P < 0.0001). There was no significant increase in inflammation or prednisolone dosage following SLT. We compared the success group, which demonstrated successful IOP reduction after 6 months of SLT, to the other failure group. The success group had shorter uveitis duration (1.37 ± 0.41 vs. 1.97 ± 0.80 years, P = 0.032) and lower baseline IOP (25.5 ± 5.09 vs. 33.7 ± 5.57 mmHg, P = 0.035). This study found that SLT had a positive IOP-lowering effect and was safe in patients with uveitic glaucoma who had not responded to medical treatment. |
| format | Article |
| id | doaj-art-a3b1354a40334e4dbda49db0332fcc0e |
| institution | Kabale University |
| issn | 2045-2322 |
| language | English |
| publishDate | 2025-02-01 |
| publisher | Nature Portfolio |
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| series | Scientific Reports |
| spelling | doaj-art-a3b1354a40334e4dbda49db0332fcc0e2025-02-09T12:30:43ZengNature PortfolioScientific Reports2045-23222025-02-011511710.1038/s41598-025-88354-0Efficacy and safety of selective laser trabeculoplasty for uveitic glaucomaMinako Suzuki0Masaki Takeuchi1Akira Meguro2Jutaro Nakamura3Mamoru Tateishi4Miki Fukuda5Akihiro Kamata6Yuki Mizuki7Kayoko Yamada8Etsuko Shibuya9Norihiro Yamada10Mami Ishihara11Nobuhisa Mizuki12Department of Ophthalmology and Visual Science, Yokohama City University Graduate School of MedicineDepartment of Ophthalmology and Visual Science, Yokohama City University Graduate School of MedicineDepartment of Ophthalmology and Visual Science, Yokohama City University Graduate School of MedicineDepartment of Ophthalmology and Visual Science, Yokohama City University Graduate School of MedicineDepartment of Ophthalmology and Visual Science, Yokohama City University Graduate School of MedicineDepartment of Ophthalmology and Visual Science, Yokohama City University Graduate School of MedicineDepartment of Ophthalmology and Visual Science, Yokohama City University Graduate School of MedicineDepartment of Ophthalmology and Visual Science, Yokohama City University Graduate School of MedicineDepartment of Ophthalmology and Visual Science, Yokohama City University Graduate School of MedicineDepartment of Ophthalmology and Visual Science, Yokohama City University Graduate School of MedicineDepartment of Ophthalmology and Visual Science, Yokohama City University Graduate School of MedicineDepartment of Ophthalmology and Visual Science, Yokohama City University Graduate School of MedicineDepartment of Ophthalmology and Visual Science, Yokohama City University Graduate School of MedicineAbstract To determine the efficacy and safety of selective laser trabeculoplasty (SLT) in patients with uveitic glaucoma, we retrospectively evaluated 17 eyes from 13 consecutive uveitic glaucoma cases who were treated with SLT due to inadequate interocular pressure (IOP) control despite glaucoma medical therapy. The mean IOP was significantly decreased from 28.4 ± 6.50 mmHg to 17.3 ± 9.4 mmHg at baseline, and 6 months after SLT, respectively (P < 0.0001). There was no significant increase in inflammation or prednisolone dosage following SLT. We compared the success group, which demonstrated successful IOP reduction after 6 months of SLT, to the other failure group. The success group had shorter uveitis duration (1.37 ± 0.41 vs. 1.97 ± 0.80 years, P = 0.032) and lower baseline IOP (25.5 ± 5.09 vs. 33.7 ± 5.57 mmHg, P = 0.035). This study found that SLT had a positive IOP-lowering effect and was safe in patients with uveitic glaucoma who had not responded to medical treatment.https://doi.org/10.1038/s41598-025-88354-0 |
| spellingShingle | Minako Suzuki Masaki Takeuchi Akira Meguro Jutaro Nakamura Mamoru Tateishi Miki Fukuda Akihiro Kamata Yuki Mizuki Kayoko Yamada Etsuko Shibuya Norihiro Yamada Mami Ishihara Nobuhisa Mizuki Efficacy and safety of selective laser trabeculoplasty for uveitic glaucoma Scientific Reports |
| title | Efficacy and safety of selective laser trabeculoplasty for uveitic glaucoma |
| title_full | Efficacy and safety of selective laser trabeculoplasty for uveitic glaucoma |
| title_fullStr | Efficacy and safety of selective laser trabeculoplasty for uveitic glaucoma |
| title_full_unstemmed | Efficacy and safety of selective laser trabeculoplasty for uveitic glaucoma |
| title_short | Efficacy and safety of selective laser trabeculoplasty for uveitic glaucoma |
| title_sort | efficacy and safety of selective laser trabeculoplasty for uveitic glaucoma |
| url | https://doi.org/10.1038/s41598-025-88354-0 |
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