Functional interactions between KCNE1 C-terminus and the KCNQ1 channel.

Functional interactions between KCNE1 C-terminus and the KCNQ1 channel.

The KCNE1 gene product (minK protein) associates with the cardiac KvLQT1 potassium channel (encoded by KCNQ1) to create the cardiac slowly activating delayed rectifier, I(Ks). Mutations throughout both genes are linked to the hereditary cardiac arrhythmias in the Long QT Syndrome (LQTS). KCNE1 exert...

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Bibliographic Details
Main Authors: Jerri Chen, Renjian Zheng, Yonathan F Melman, Thomas V McDonald
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0005143&type=printable
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