The Role of Vitamin C Supplementation in Preventing Severity Progression in Mild and Moderate COVID-19 Patients at Universitas Airlangga Hospital
Introduction: Coronavirus disease (COVID-19) is an infectious disease that increases pro-oxidant elements and decreases antioxidants. Vitamin C functions as a potent antioxidant in humans due to its electron-donating properties. This study aimed to explain the impact of three distinct vitamin C sup...
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Fakultas Kedokteran Universitas Airlangga
2025-01-01
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| Series: | Juxta: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga |
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| Online Access: | https://e-journal.unair.ac.id/JUXTA/article/view/60284 |
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| author | Yoga Akbar Arifandi Alfian Nur Rosyid Danti Nur Indiastuti Wiwin Is Effendi |
| author_facet | Yoga Akbar Arifandi Alfian Nur Rosyid Danti Nur Indiastuti Wiwin Is Effendi |
| author_sort | Yoga Akbar Arifandi |
| collection | DOAJ |
| description | Introduction: Coronavirus disease (COVID-19) is an infectious disease that increases pro-oxidant elements and decreases antioxidants. Vitamin C functions as a potent antioxidant in humans due to its electron-donating properties. This study aimed to explain the impact of three distinct vitamin C supplementation dosages in preventing disease severity progression among mild and moderate COVID-19 patients.
Methods: This retrospective study used secondary data from 100 medical records (n=100). The subjects were classified into three categories based on the vitamin C dosage. The data were analyzed using the International Business Machines Corporation (IBM) Statistical Package for Social Sciences (SPSS) version 26.0 for Windows.
Results: Most of mild and moderate COVID-19 patients (78%) did not experience increased disease severity. Vitamin C supplementation significantly demonstrated a different outcome in preventing disease severity progression among the three groups (p=0.018). However, it did not significantly show any difference in reducing the duration of hospital stay (p=0.680).
Conclusion: The impact of vitamin C supplementation on COVID-19 severity appeared to vary depending on the dosage administered. However, it did not affect the duration of the hospital stay. |
| format | Article |
| id | doaj-art-a3a5e3daf1e446b4b55efe89c4e55dd5 |
| institution | OA Journals |
| issn | 1907-3623 2684-9453 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Fakultas Kedokteran Universitas Airlangga |
| record_format | Article |
| series | Juxta: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga |
| spelling | doaj-art-a3a5e3daf1e446b4b55efe89c4e55dd52025-08-20T02:11:04ZengFakultas Kedokteran Universitas AirlanggaJuxta: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga1907-36232684-94532025-01-011616369https://doi.org/10.20473/juxta.V16I12025.63-69The Role of Vitamin C Supplementation in Preventing Severity Progression in Mild and Moderate COVID-19 Patients at Universitas Airlangga HospitalYoga Akbar Arifandi0https://orcid.org/0009-0002-9357-8348Alfian Nur Rosyid1https://orcid.org/0000-0001-7042-996XDanti Nur Indiastuti2https://orcid.org/0000-0002-1815-1224Wiwin Is Effendi3https://orcid.org/0000-0003-3716-2452Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia.Department of Pulmonology and Respiratory Medicine, Faculty of Medicine, Universitas Airlangga/Universitas Airlangga Hospital, Surabaya, Indonesia.Department of Anatomy, Histology, and Pharmacology, Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia.The Indonesian Society of Respirology (PDPI) East Java Chapter, Surabaya, Indonesia.Introduction: Coronavirus disease (COVID-19) is an infectious disease that increases pro-oxidant elements and decreases antioxidants. Vitamin C functions as a potent antioxidant in humans due to its electron-donating properties. This study aimed to explain the impact of three distinct vitamin C supplementation dosages in preventing disease severity progression among mild and moderate COVID-19 patients. Methods: This retrospective study used secondary data from 100 medical records (n=100). The subjects were classified into three categories based on the vitamin C dosage. The data were analyzed using the International Business Machines Corporation (IBM) Statistical Package for Social Sciences (SPSS) version 26.0 for Windows. Results: Most of mild and moderate COVID-19 patients (78%) did not experience increased disease severity. Vitamin C supplementation significantly demonstrated a different outcome in preventing disease severity progression among the three groups (p=0.018). However, it did not significantly show any difference in reducing the duration of hospital stay (p=0.680). Conclusion: The impact of vitamin C supplementation on COVID-19 severity appeared to vary depending on the dosage administered. However, it did not affect the duration of the hospital stay.https://e-journal.unair.ac.id/JUXTA/article/view/60284antioxidantcovid-19infectious diseasevitamin c |
| spellingShingle | Yoga Akbar Arifandi Alfian Nur Rosyid Danti Nur Indiastuti Wiwin Is Effendi The Role of Vitamin C Supplementation in Preventing Severity Progression in Mild and Moderate COVID-19 Patients at Universitas Airlangga Hospital Juxta: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga antioxidant covid-19 infectious disease vitamin c |
| title | The Role of Vitamin C Supplementation in Preventing Severity Progression in Mild and Moderate COVID-19 Patients at Universitas Airlangga Hospital |
| title_full | The Role of Vitamin C Supplementation in Preventing Severity Progression in Mild and Moderate COVID-19 Patients at Universitas Airlangga Hospital |
| title_fullStr | The Role of Vitamin C Supplementation in Preventing Severity Progression in Mild and Moderate COVID-19 Patients at Universitas Airlangga Hospital |
| title_full_unstemmed | The Role of Vitamin C Supplementation in Preventing Severity Progression in Mild and Moderate COVID-19 Patients at Universitas Airlangga Hospital |
| title_short | The Role of Vitamin C Supplementation in Preventing Severity Progression in Mild and Moderate COVID-19 Patients at Universitas Airlangga Hospital |
| title_sort | role of vitamin c supplementation in preventing severity progression in mild and moderate covid 19 patients at universitas airlangga hospital |
| topic | antioxidant covid-19 infectious disease vitamin c |
| url | https://e-journal.unair.ac.id/JUXTA/article/view/60284 |
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