Knowledge, attitude, and practice among community pharmacists toward adverse drug reaction reporting and pharmacovigilance: A nationwide survey

Background: To enhance the impact of pharmacovigilance on drug safety, it must be integrated into the healthcare system. This study aimed to examine community pharmacists' knowledge, attitudes, and practices regarding adverse drug reaction reporting and pharmacovigilance. Methods: A self-admini...

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Main Authors: Tahani Alwidyan, Mohannad Odeh, Ameerah Hasan Ibrahim, Eman Harahsheh, Aya Banat
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:Exploratory Research in Clinical and Social Pharmacy
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Online Access:http://www.sciencedirect.com/science/article/pii/S2667276625000198
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author Tahani Alwidyan
Mohannad Odeh
Ameerah Hasan Ibrahim
Eman Harahsheh
Aya Banat
author_facet Tahani Alwidyan
Mohannad Odeh
Ameerah Hasan Ibrahim
Eman Harahsheh
Aya Banat
author_sort Tahani Alwidyan
collection DOAJ
description Background: To enhance the impact of pharmacovigilance on drug safety, it must be integrated into the healthcare system. This study aimed to examine community pharmacists' knowledge, attitudes, and practices regarding adverse drug reaction reporting and pharmacovigilance. Methods: A self-administered, cross-sectional questionnaire study was conducted among eligible community pharmacists between July and September 2023. Participants completed online and paper-based questionnaires after providing prior consent. Descriptive and inferential analyses were performed using the Statistical Package for Social Sciences (SPSS, version 28). One-way ANOVA was used to assess the significance of the association between knowledge, attitude, practice scores, and demographic characteristics. Results: A total of 239 pharmacists completed the questionnaire (response rate of 67.5 %). Of them, 65.3 % were females. Poor knowledge regarding pharmacovigilance was evident in 66.1 % of participants, while only 11 % demonstrated good knowledge. Attitudes were primarily neutral (72.8 %), and practices were categorized as fair for 41.0 % and poor for 31.0 % of pharmacists. Significant factors influencing adverse drug reaction reporting included years of experience (P = 0.012) and awareness of the pharmacovigilance center (P = 0.000). The serious nature of adverse drug reactions was identified as the key facilitator for reporting (40.5 %), while well-documented adverse drug reactions in the literature (21.2 %) and lack of time (19.5 %) were the primary barriers among pharmacists. Conclusion: This study emphasizes the potential enhancement of adverse drug reaction reporting among community pharmacists by addressing poor knowledge, neutral attitudes, and barriers like time constraints. Targeted educational interventions and structured reporting frameworks are essential to enhance pharmacovigilance and ensure medication safety.
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spelling doaj-art-a3a1cd014cdc4ac3aceb519a20e263ce2025-08-20T03:49:41ZengElsevierExploratory Research in Clinical and Social Pharmacy2667-27662025-06-011810057810.1016/j.rcsop.2025.100578Knowledge, attitude, and practice among community pharmacists toward adverse drug reaction reporting and pharmacovigilance: A nationwide surveyTahani Alwidyan0Mohannad Odeh1Ameerah Hasan Ibrahim2Eman Harahsheh3Aya Banat4Department of Clinical Pharmacy and Pharmacy Practice, Faculty of Pharmaceutical Sciences, The Hashemite University, Zarqa, Jordan; Corresponding author at: Department of Clinical Pharmacy and Pharmacy Practice, Faculty of Pharmaceutical Sciences, The Hashemite University, Damascus Hwy Road, Zarqa 13133, P.O. Box 330127, Jordan.Department of Clinical Pharmacy and Pharmacy Practice, Faculty of Pharmaceutical Sciences, The Hashemite University, Zarqa, JordanDepartment of Pharmacy, Faculty of Pharmacy, Al-Zaytoonah University of Jordan, Amman, JordanDepartment of Clinical Pharmacy and Pharmacy Practice, Faculty of Pharmaceutical Sciences, The Hashemite University, Zarqa, JordanDepartment of Clinical Pharmacy and Pharmacy Practice, Faculty of Pharmaceutical Sciences, The Hashemite University, Zarqa, JordanBackground: To enhance the impact of pharmacovigilance on drug safety, it must be integrated into the healthcare system. This study aimed to examine community pharmacists' knowledge, attitudes, and practices regarding adverse drug reaction reporting and pharmacovigilance. Methods: A self-administered, cross-sectional questionnaire study was conducted among eligible community pharmacists between July and September 2023. Participants completed online and paper-based questionnaires after providing prior consent. Descriptive and inferential analyses were performed using the Statistical Package for Social Sciences (SPSS, version 28). One-way ANOVA was used to assess the significance of the association between knowledge, attitude, practice scores, and demographic characteristics. Results: A total of 239 pharmacists completed the questionnaire (response rate of 67.5 %). Of them, 65.3 % were females. Poor knowledge regarding pharmacovigilance was evident in 66.1 % of participants, while only 11 % demonstrated good knowledge. Attitudes were primarily neutral (72.8 %), and practices were categorized as fair for 41.0 % and poor for 31.0 % of pharmacists. Significant factors influencing adverse drug reaction reporting included years of experience (P = 0.012) and awareness of the pharmacovigilance center (P = 0.000). The serious nature of adverse drug reactions was identified as the key facilitator for reporting (40.5 %), while well-documented adverse drug reactions in the literature (21.2 %) and lack of time (19.5 %) were the primary barriers among pharmacists. Conclusion: This study emphasizes the potential enhancement of adverse drug reaction reporting among community pharmacists by addressing poor knowledge, neutral attitudes, and barriers like time constraints. Targeted educational interventions and structured reporting frameworks are essential to enhance pharmacovigilance and ensure medication safety.http://www.sciencedirect.com/science/article/pii/S2667276625000198PharmacovigilanceAdverse drug reaction reportingCommunity pharmacistsKnowledgeAttitudePractice
spellingShingle Tahani Alwidyan
Mohannad Odeh
Ameerah Hasan Ibrahim
Eman Harahsheh
Aya Banat
Knowledge, attitude, and practice among community pharmacists toward adverse drug reaction reporting and pharmacovigilance: A nationwide survey
Exploratory Research in Clinical and Social Pharmacy
Pharmacovigilance
Adverse drug reaction reporting
Community pharmacists
Knowledge
Attitude
Practice
title Knowledge, attitude, and practice among community pharmacists toward adverse drug reaction reporting and pharmacovigilance: A nationwide survey
title_full Knowledge, attitude, and practice among community pharmacists toward adverse drug reaction reporting and pharmacovigilance: A nationwide survey
title_fullStr Knowledge, attitude, and practice among community pharmacists toward adverse drug reaction reporting and pharmacovigilance: A nationwide survey
title_full_unstemmed Knowledge, attitude, and practice among community pharmacists toward adverse drug reaction reporting and pharmacovigilance: A nationwide survey
title_short Knowledge, attitude, and practice among community pharmacists toward adverse drug reaction reporting and pharmacovigilance: A nationwide survey
title_sort knowledge attitude and practice among community pharmacists toward adverse drug reaction reporting and pharmacovigilance a nationwide survey
topic Pharmacovigilance
Adverse drug reaction reporting
Community pharmacists
Knowledge
Attitude
Practice
url http://www.sciencedirect.com/science/article/pii/S2667276625000198
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