Implant-Related Infection in the Tibia: Surgical Revision Strategy with Vancomycin Cement
The development of a deep wound infection in the presence of internal hardware presents a clinical dilemma. The purpose of the present study was to evaluate the treatment outcomes of vancomycin cement with other advances of surgical techniques for implant-related infection (IRI) in the tibia. This s...
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| Format: | Article |
| Language: | English |
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Wiley
2014-01-01
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| Series: | The Scientific World Journal |
| Online Access: | http://dx.doi.org/10.1155/2014/124864 |
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| author | Yong-Qing Xu Yue-Liang Zhu Xin-Yv Fan Tao Jin Yang Li Xiao-Qing He |
| author_facet | Yong-Qing Xu Yue-Liang Zhu Xin-Yv Fan Tao Jin Yang Li Xiao-Qing He |
| author_sort | Yong-Qing Xu |
| collection | DOAJ |
| description | The development of a deep wound infection in the presence of internal hardware presents a clinical dilemma. The purpose of the present study was to evaluate the treatment outcomes of vancomycin cement with other advances of surgical techniques for implant-related infection (IRI) in the tibia. This study included 217 consecutive patients who had sustained IRI of the tibia. Of them, 152 patients had soft tissue defects and the internal hardware was exposed. Repeated debridement and negative pressure assisted closure were used. All the infected internal hardware was removed. External fixations and flaps were used. Custom-made vancomycin cement was inserted into the dead space of the wounds and left in site for a month. The follow-up was from 12 months to 108 months, averaging 37.5 months. For all the 217 patients, the general osteomyelitis healing rate and bone union rate were 86.6% and 97.2%, respectively. This study shows high rates of healing of IRI in the tibia if the new advances of surgery could be effectively combined into the treatment strategy with vancomycin cement as an important treatment. |
| format | Article |
| id | doaj-art-a3a005e0f15542bda7ac19e56768407e |
| institution | Kabale University |
| issn | 2356-6140 1537-744X |
| language | English |
| publishDate | 2014-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | The Scientific World Journal |
| spelling | doaj-art-a3a005e0f15542bda7ac19e56768407e2025-08-20T03:38:25ZengWileyThe Scientific World Journal2356-61401537-744X2014-01-01201410.1155/2014/124864124864Implant-Related Infection in the Tibia: Surgical Revision Strategy with Vancomycin CementYong-Qing Xu0Yue-Liang Zhu1Xin-Yv Fan2Tao Jin3Yang Li4Xiao-Qing He5Orthopaedic Department, Kunming General Hospital of Chengdu Military Region, No. 212, Daguan Road, Kunming, Yunnan 650032, ChinaOrthopaedic Department, Kunming General Hospital of Chengdu Military Region, No. 212, Daguan Road, Kunming, Yunnan 650032, ChinaOrthopaedic Department, Kunming General Hospital of Chengdu Military Region, No. 212, Daguan Road, Kunming, Yunnan 650032, ChinaOrthopaedic Department, Kunming General Hospital of Chengdu Military Region, No. 212, Daguan Road, Kunming, Yunnan 650032, ChinaOrthopaedic Department, Kunming General Hospital of Chengdu Military Region, No. 212, Daguan Road, Kunming, Yunnan 650032, ChinaOrthopaedic Department, Kunming General Hospital of Chengdu Military Region, No. 212, Daguan Road, Kunming, Yunnan 650032, ChinaThe development of a deep wound infection in the presence of internal hardware presents a clinical dilemma. The purpose of the present study was to evaluate the treatment outcomes of vancomycin cement with other advances of surgical techniques for implant-related infection (IRI) in the tibia. This study included 217 consecutive patients who had sustained IRI of the tibia. Of them, 152 patients had soft tissue defects and the internal hardware was exposed. Repeated debridement and negative pressure assisted closure were used. All the infected internal hardware was removed. External fixations and flaps were used. Custom-made vancomycin cement was inserted into the dead space of the wounds and left in site for a month. The follow-up was from 12 months to 108 months, averaging 37.5 months. For all the 217 patients, the general osteomyelitis healing rate and bone union rate were 86.6% and 97.2%, respectively. This study shows high rates of healing of IRI in the tibia if the new advances of surgery could be effectively combined into the treatment strategy with vancomycin cement as an important treatment.http://dx.doi.org/10.1155/2014/124864 |
| spellingShingle | Yong-Qing Xu Yue-Liang Zhu Xin-Yv Fan Tao Jin Yang Li Xiao-Qing He Implant-Related Infection in the Tibia: Surgical Revision Strategy with Vancomycin Cement The Scientific World Journal |
| title | Implant-Related Infection in the Tibia: Surgical Revision Strategy with Vancomycin Cement |
| title_full | Implant-Related Infection in the Tibia: Surgical Revision Strategy with Vancomycin Cement |
| title_fullStr | Implant-Related Infection in the Tibia: Surgical Revision Strategy with Vancomycin Cement |
| title_full_unstemmed | Implant-Related Infection in the Tibia: Surgical Revision Strategy with Vancomycin Cement |
| title_short | Implant-Related Infection in the Tibia: Surgical Revision Strategy with Vancomycin Cement |
| title_sort | implant related infection in the tibia surgical revision strategy with vancomycin cement |
| url | http://dx.doi.org/10.1155/2014/124864 |
| work_keys_str_mv | AT yongqingxu implantrelatedinfectioninthetibiasurgicalrevisionstrategywithvancomycincement AT yueliangzhu implantrelatedinfectioninthetibiasurgicalrevisionstrategywithvancomycincement AT xinyvfan implantrelatedinfectioninthetibiasurgicalrevisionstrategywithvancomycincement AT taojin implantrelatedinfectioninthetibiasurgicalrevisionstrategywithvancomycincement AT yangli implantrelatedinfectioninthetibiasurgicalrevisionstrategywithvancomycincement AT xiaoqinghe implantrelatedinfectioninthetibiasurgicalrevisionstrategywithvancomycincement |