Symptomatic therapy for ankylosing spondylitis

The paper characterizes ankylosing spondylitis (AS), one of the common spinal inflammatory diseases, in which not only sacroiliac, peripheral, and root (shoulder and hip) joints, but also the aorta, heart valve apparatus, myocardium, bronchopulmonary system, kidneys, nerve system, and the organ of v...

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Main Author: Vladimir Vasilyevich Badokin
Format: Article
Language:Russian
Published: IMA-PRESS LLC 2012-03-01
Series:Современная ревматология
Subjects:
Online Access:https://mrj.ima-press.net/mrj/article/view/405
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author Vladimir Vasilyevich Badokin
author_facet Vladimir Vasilyevich Badokin
author_sort Vladimir Vasilyevich Badokin
collection DOAJ
description The paper characterizes ankylosing spondylitis (AS), one of the common spinal inflammatory diseases, in which not only sacroiliac, peripheral, and root (shoulder and hip) joints, but also the aorta, heart valve apparatus, myocardium, bronchopulmonary system, kidneys, nerve system, and the organ of vision are involved in the pathological process. It is stated that the relatively high prevalence of AS, its young onset, progressively reduced spinal mobility, and early disability in the patients require active anti-inflammatory therapy. Significant progress in the treatment of AS is associated with the introduction of gene engineering biologicals into clinical practice. At the same time symptomatic therapy (nonsteroidal anti-inflammatory drugs, glucocorticoids, simple analgesics, myorelaxants) is noted to play an important role in AS. Myorelaxants actively affect not only the major manifestations (pain and rigidity) of AS, but also the functional state of the locomotor apparatus and the outcome of the disease as a whole. By reducing muscle tone and the degree of rigidity, they contribute to increased movement amplitudes in the spine and peripheral joints. Among the drugs of this group, the central myorelaxant mydocalm is most commonly used in Russia.
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spelling doaj-art-a39a8cd1ea77425bb4824ddc45a0e2732025-08-20T03:21:01ZrusIMA-PRESS LLCСовременная ревматология1996-70122310-158X2012-03-0161697410.14412/1996-7012-2012-7201710Symptomatic therapy for ankylosing spondylitisVladimir Vasilyevich BadokinThe paper characterizes ankylosing spondylitis (AS), one of the common spinal inflammatory diseases, in which not only sacroiliac, peripheral, and root (shoulder and hip) joints, but also the aorta, heart valve apparatus, myocardium, bronchopulmonary system, kidneys, nerve system, and the organ of vision are involved in the pathological process. It is stated that the relatively high prevalence of AS, its young onset, progressively reduced spinal mobility, and early disability in the patients require active anti-inflammatory therapy. Significant progress in the treatment of AS is associated with the introduction of gene engineering biologicals into clinical practice. At the same time symptomatic therapy (nonsteroidal anti-inflammatory drugs, glucocorticoids, simple analgesics, myorelaxants) is noted to play an important role in AS. Myorelaxants actively affect not only the major manifestations (pain and rigidity) of AS, but also the functional state of the locomotor apparatus and the outcome of the disease as a whole. By reducing muscle tone and the degree of rigidity, they contribute to increased movement amplitudes in the spine and peripheral joints. Among the drugs of this group, the central myorelaxant mydocalm is most commonly used in Russia.https://mrj.ima-press.net/mrj/article/view/405ankylosing spondylitisanti-inflammatory therapysymptomatic treatmentmyorelaxants
spellingShingle Vladimir Vasilyevich Badokin
Symptomatic therapy for ankylosing spondylitis
Современная ревматология
ankylosing spondylitis
anti-inflammatory therapy
symptomatic treatment
myorelaxants
title Symptomatic therapy for ankylosing spondylitis
title_full Symptomatic therapy for ankylosing spondylitis
title_fullStr Symptomatic therapy for ankylosing spondylitis
title_full_unstemmed Symptomatic therapy for ankylosing spondylitis
title_short Symptomatic therapy for ankylosing spondylitis
title_sort symptomatic therapy for ankylosing spondylitis
topic ankylosing spondylitis
anti-inflammatory therapy
symptomatic treatment
myorelaxants
url https://mrj.ima-press.net/mrj/article/view/405
work_keys_str_mv AT vladimirvasilyevichbadokin symptomatictherapyforankylosingspondylitis