Deciphering functional landscape and clinical implications of enhancer RNAs in lung adenocarcinoma

Deciphering functional landscape and clinical implications of enhancer RNAs in lung adenocarcinoma

Abstract Lung adenocarcinoma (LUAD) is a common and deadly subtype of lung cancer with high mortality and limited treatment options. Enhancer RNAs (eRNAs) have emerged as important regulators in cancer biology, but their specific roles in LUAD have not been fully explored. This study aimed to invest...

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Bibliographic Details
Main Authors: Aike Li, Liguang Zhang, Xinsheng Du, Yi Dong, Yan Guo, Jiwei Zhao, Xiuli Fang, Pingping Lin
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:Scientific Reports
Subjects:
Lung adenocarcinoma (LUAD)
Enhancer RNAs (eRNAs)
Bioinformatics
Transcription factor (TF)
Online Access:https://doi.org/10.1038/s41598-025-15485-9
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