A true malignant mixed tumour of the parotid gland

Salivary gland carcinosarcomas contain both malignant epithelial and mesenchymal elements making them a true malignant mixed tumour. They may arise ‘de novo’ or from an existing pleomorphic adenoma and are often difficult to diagnose histologically. Management is by means of radical surgery, but pro...

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Main Authors: Ayesha McLennan-Dalal, Efstathia Kyrodimou, Sarah L. Saunders, Syed Ali Khurram, Andrew S. McLennan
Format: Article
Language:English
Published: Elsevier 2025-03-01
Series:Advances in Oral and Maxillofacial Surgery
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Online Access:http://www.sciencedirect.com/science/article/pii/S2667147625000081
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author Ayesha McLennan-Dalal
Efstathia Kyrodimou
Sarah L. Saunders
Syed Ali Khurram
Andrew S. McLennan
author_facet Ayesha McLennan-Dalal
Efstathia Kyrodimou
Sarah L. Saunders
Syed Ali Khurram
Andrew S. McLennan
author_sort Ayesha McLennan-Dalal
collection DOAJ
description Salivary gland carcinosarcomas contain both malignant epithelial and mesenchymal elements making them a true malignant mixed tumour. They may arise ‘de novo’ or from an existing pleomorphic adenoma and are often difficult to diagnose histologically. Management is by means of radical surgery, but prognosis remains poor. We present a case of this rare tumour seen in a young patient to highlight its aggressive potential.
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institution Kabale University
issn 2667-1476
language English
publishDate 2025-03-01
publisher Elsevier
record_format Article
series Advances in Oral and Maxillofacial Surgery
spelling doaj-art-a397843dcf6b49259387db65f9296fa22025-02-07T04:48:30ZengElsevierAdvances in Oral and Maxillofacial Surgery2667-14762025-03-0117100521A true malignant mixed tumour of the parotid glandAyesha McLennan-Dalal0Efstathia Kyrodimou1Sarah L. Saunders2Syed Ali Khurram3Andrew S. McLennan4Specialty Registrar Oral and Maxillofacial Surgery, Royal Devon University Healthcare NHSFT, UK; Corresponding author.Consultant Histopathologist, Royal Devon University Healthcare NHSFT, UKConsultant Histopathologist, Royal Devon University Healthcare NHSFT, UKConsultant Oral and Maxillofacial Pathologist, School of Clinical Dentistry, University of Sheffield, UKConsultant Oral and Maxillofacial Surgeon, Royal Devon University Healthcare NHSFT, UKSalivary gland carcinosarcomas contain both malignant epithelial and mesenchymal elements making them a true malignant mixed tumour. They may arise ‘de novo’ or from an existing pleomorphic adenoma and are often difficult to diagnose histologically. Management is by means of radical surgery, but prognosis remains poor. We present a case of this rare tumour seen in a young patient to highlight its aggressive potential.http://www.sciencedirect.com/science/article/pii/S2667147625000081CarcinosarcomaOsteosarcomaCarcinosarcoma ex-pleomorphic adenomaPleomorphic adenomaParotid tumour
spellingShingle Ayesha McLennan-Dalal
Efstathia Kyrodimou
Sarah L. Saunders
Syed Ali Khurram
Andrew S. McLennan
A true malignant mixed tumour of the parotid gland
Advances in Oral and Maxillofacial Surgery
Carcinosarcoma
Osteosarcoma
Carcinosarcoma ex-pleomorphic adenoma
Pleomorphic adenoma
Parotid tumour
title A true malignant mixed tumour of the parotid gland
title_full A true malignant mixed tumour of the parotid gland
title_fullStr A true malignant mixed tumour of the parotid gland
title_full_unstemmed A true malignant mixed tumour of the parotid gland
title_short A true malignant mixed tumour of the parotid gland
title_sort true malignant mixed tumour of the parotid gland
topic Carcinosarcoma
Osteosarcoma
Carcinosarcoma ex-pleomorphic adenoma
Pleomorphic adenoma
Parotid tumour
url http://www.sciencedirect.com/science/article/pii/S2667147625000081
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