Raphe-Type Bicuspid Aortic Valve as a Risk Factor for Transcatheter Aortic Valve Replacement Failure: Improving Outcomes Using the LIRA Method and the Medtronic FX Prosthesis
Transcatheter aortic valve replacement (TAVR) in patients with severe aortic stenosis and raphe-type bicuspid aortic valve (BAV) is still associated with poor outcomes in terms of increased risk of paravalvular regurgitation, stroke, and permanent pacemaker implantation. There is no definitive conse...
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MDPI AG
2024-12-01
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| Series: | Journal of Cardiovascular Development and Disease |
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| Online Access: | https://www.mdpi.com/2308-3425/12/1/11 |
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| author | Francesca Napoli Barbara Bellini Vittorio Romano Greca Zanda Ciro Vella Filippo Russo Luca Angelo Ferri Marco Bruno Ancona Paolo Bonfanti Eustachio Agricola Antonio Esposito Matteo Montorfano |
| author_facet | Francesca Napoli Barbara Bellini Vittorio Romano Greca Zanda Ciro Vella Filippo Russo Luca Angelo Ferri Marco Bruno Ancona Paolo Bonfanti Eustachio Agricola Antonio Esposito Matteo Montorfano |
| author_sort | Francesca Napoli |
| collection | DOAJ |
| description | Transcatheter aortic valve replacement (TAVR) in patients with severe aortic stenosis and raphe-type bicuspid aortic valve (BAV) is still associated with poor outcomes in terms of increased risk of paravalvular regurgitation, stroke, and permanent pacemaker implantation. There is no definitive consensus on the optimal sizing method for prosthesis selection in this setting. The LIRA method is a supra-annular tailored sizing method specifically designed for bicuspid anatomy that might increase accuracy of prosthesis choice in BAV patients and improve TAVR outcomes. This is the first report of the combination of the novel LIRA method for prosthesis sizing together with the adoption of the technological improvements introduced by the Evolut FX prosthesis as a useful tool for improving outcomes in this high risk subgroup of patients. |
| format | Article |
| id | doaj-art-a3965f9c1d1742e4ba44a7d262723c2e |
| institution | Kabale University |
| issn | 2308-3425 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Cardiovascular Development and Disease |
| spelling | doaj-art-a3965f9c1d1742e4ba44a7d262723c2e2025-01-24T13:35:58ZengMDPI AGJournal of Cardiovascular Development and Disease2308-34252024-12-011211110.3390/jcdd12010011Raphe-Type Bicuspid Aortic Valve as a Risk Factor for Transcatheter Aortic Valve Replacement Failure: Improving Outcomes Using the LIRA Method and the Medtronic FX ProsthesisFrancesca Napoli0Barbara Bellini1Vittorio Romano2Greca Zanda3Ciro Vella4Filippo Russo5Luca Angelo Ferri6Marco Bruno Ancona7Paolo Bonfanti8Eustachio Agricola9Antonio Esposito10Matteo Montorfano11Interventional Cardiology Unit, IRCCS San Raffaele Scientific Institute, 20132 Milan, ItalyInterventional Cardiology Unit, IRCCS San Raffaele Scientific Institute, 20132 Milan, ItalyInterventional Cardiology Unit, IRCCS San Raffaele Scientific Institute, 20132 Milan, ItalyInterventional Cardiology Unit, IRCCS San Raffaele Scientific Institute, 20132 Milan, ItalyInterventional Cardiology Unit, IRCCS San Raffaele Scientific Institute, 20132 Milan, ItalyInterventional Cardiology Unit, IRCCS San Raffaele Scientific Institute, 20132 Milan, ItalyInterventional Cardiology Unit, IRCCS San Raffaele Scientific Institute, 20132 Milan, ItalyInterventional Cardiology Unit, IRCCS San Raffaele Scientific Institute, 20132 Milan, ItalyComplex Unit of Cardiology, Ospedale Valduce, 22100 Como, ItalyCardiovascular Imaging Unit, IRCCS San Raffaele Scientific Institute, 20132 Milan, ItalySchool of Medicine, Vita Salute San Raffaele University, 20132 Milan, ItalyInterventional Cardiology Unit, IRCCS San Raffaele Scientific Institute, 20132 Milan, ItalyTranscatheter aortic valve replacement (TAVR) in patients with severe aortic stenosis and raphe-type bicuspid aortic valve (BAV) is still associated with poor outcomes in terms of increased risk of paravalvular regurgitation, stroke, and permanent pacemaker implantation. There is no definitive consensus on the optimal sizing method for prosthesis selection in this setting. The LIRA method is a supra-annular tailored sizing method specifically designed for bicuspid anatomy that might increase accuracy of prosthesis choice in BAV patients and improve TAVR outcomes. This is the first report of the combination of the novel LIRA method for prosthesis sizing together with the adoption of the technological improvements introduced by the Evolut FX prosthesis as a useful tool for improving outcomes in this high risk subgroup of patients.https://www.mdpi.com/2308-3425/12/1/11bicuspid aortic valveLIRA methodtranscatheter aortic valve replacement |
| spellingShingle | Francesca Napoli Barbara Bellini Vittorio Romano Greca Zanda Ciro Vella Filippo Russo Luca Angelo Ferri Marco Bruno Ancona Paolo Bonfanti Eustachio Agricola Antonio Esposito Matteo Montorfano Raphe-Type Bicuspid Aortic Valve as a Risk Factor for Transcatheter Aortic Valve Replacement Failure: Improving Outcomes Using the LIRA Method and the Medtronic FX Prosthesis Journal of Cardiovascular Development and Disease bicuspid aortic valve LIRA method transcatheter aortic valve replacement |
| title | Raphe-Type Bicuspid Aortic Valve as a Risk Factor for Transcatheter Aortic Valve Replacement Failure: Improving Outcomes Using the LIRA Method and the Medtronic FX Prosthesis |
| title_full | Raphe-Type Bicuspid Aortic Valve as a Risk Factor for Transcatheter Aortic Valve Replacement Failure: Improving Outcomes Using the LIRA Method and the Medtronic FX Prosthesis |
| title_fullStr | Raphe-Type Bicuspid Aortic Valve as a Risk Factor for Transcatheter Aortic Valve Replacement Failure: Improving Outcomes Using the LIRA Method and the Medtronic FX Prosthesis |
| title_full_unstemmed | Raphe-Type Bicuspid Aortic Valve as a Risk Factor for Transcatheter Aortic Valve Replacement Failure: Improving Outcomes Using the LIRA Method and the Medtronic FX Prosthesis |
| title_short | Raphe-Type Bicuspid Aortic Valve as a Risk Factor for Transcatheter Aortic Valve Replacement Failure: Improving Outcomes Using the LIRA Method and the Medtronic FX Prosthesis |
| title_sort | raphe type bicuspid aortic valve as a risk factor for transcatheter aortic valve replacement failure improving outcomes using the lira method and the medtronic fx prosthesis |
| topic | bicuspid aortic valve LIRA method transcatheter aortic valve replacement |
| url | https://www.mdpi.com/2308-3425/12/1/11 |
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