Artocarpus hirsutus Lam Leaf Extract-Evaluation of Analgesic and Anti-Inflammatory Activity
The study involved extraction, identification, and evaluation of pharmacological activities of the phytochemicals present. Artocarpus hirsutus Lam, commonly known as Wild jack is a greatly valued medicinal plant, which belongs to the plant family Moraceae. Preliminary phytochemical screening studies...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2022-01-01
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| Series: | Advances in Pharmacological and Pharmaceutical Sciences |
| Online Access: | http://dx.doi.org/10.1155/2022/4179487 |
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| author | M. Karthik Ullas Prakash D’Souza Prasanna Shama Khandige Vandana Sadananda S. Gowrish Savadamoorthi Kamatchi Subramani |
| author_facet | M. Karthik Ullas Prakash D’Souza Prasanna Shama Khandige Vandana Sadananda S. Gowrish Savadamoorthi Kamatchi Subramani |
| author_sort | M. Karthik |
| collection | DOAJ |
| description | The study involved extraction, identification, and evaluation of pharmacological activities of the phytochemicals present. Artocarpus hirsutus Lam, commonly known as Wild jack is a greatly valued medicinal plant, which belongs to the plant family Moraceae. Preliminary phytochemical screening studies indicated the presence of flavonoids, saponins, tannins, glycosides, and alkaloids. This study estimated the analgesic and anti-inflammatory prospective of ethanolic leaf extract of Artocarpus hirsutus Lam. The findings showed that at various doses of 100, 200, and 400 mg/kg body weight when administered orally to rats, analgesic effects were produced, also the anti-inflammatory effect studied by carrageenan-induced rat paw edema test showed major anti-inflammatory action. The result indicates that the leaf extract of Artocarpus hirsutus Lam possesses major analgesic and anti-inflammatory activity and therefore requires further investigations to better understand the mechanism of action. |
| format | Article |
| id | doaj-art-a391ea49285544a9b91cd6da036562bb |
| institution | Kabale University |
| issn | 2633-4690 |
| language | English |
| publishDate | 2022-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Advances in Pharmacological and Pharmaceutical Sciences |
| spelling | doaj-art-a391ea49285544a9b91cd6da036562bb2025-08-20T03:38:19ZengWileyAdvances in Pharmacological and Pharmaceutical Sciences2633-46902022-01-01202210.1155/2022/4179487Artocarpus hirsutus Lam Leaf Extract-Evaluation of Analgesic and Anti-Inflammatory ActivityM. Karthik0Ullas Prakash D’Souza1Prasanna Shama Khandige2Vandana Sadananda3S. Gowrish4Savadamoorthi Kamatchi Subramani5Nitte (Deemed to be University)Nitte (Deemed to be University)Nitte (Deemed to be University)Nitte (Deemed to be University)Nitte (Deemed to be University)Jazan UniversityThe study involved extraction, identification, and evaluation of pharmacological activities of the phytochemicals present. Artocarpus hirsutus Lam, commonly known as Wild jack is a greatly valued medicinal plant, which belongs to the plant family Moraceae. Preliminary phytochemical screening studies indicated the presence of flavonoids, saponins, tannins, glycosides, and alkaloids. This study estimated the analgesic and anti-inflammatory prospective of ethanolic leaf extract of Artocarpus hirsutus Lam. The findings showed that at various doses of 100, 200, and 400 mg/kg body weight when administered orally to rats, analgesic effects were produced, also the anti-inflammatory effect studied by carrageenan-induced rat paw edema test showed major anti-inflammatory action. The result indicates that the leaf extract of Artocarpus hirsutus Lam possesses major analgesic and anti-inflammatory activity and therefore requires further investigations to better understand the mechanism of action.http://dx.doi.org/10.1155/2022/4179487 |
| spellingShingle | M. Karthik Ullas Prakash D’Souza Prasanna Shama Khandige Vandana Sadananda S. Gowrish Savadamoorthi Kamatchi Subramani Artocarpus hirsutus Lam Leaf Extract-Evaluation of Analgesic and Anti-Inflammatory Activity Advances in Pharmacological and Pharmaceutical Sciences |
| title | Artocarpus hirsutus Lam Leaf Extract-Evaluation of Analgesic and Anti-Inflammatory Activity |
| title_full | Artocarpus hirsutus Lam Leaf Extract-Evaluation of Analgesic and Anti-Inflammatory Activity |
| title_fullStr | Artocarpus hirsutus Lam Leaf Extract-Evaluation of Analgesic and Anti-Inflammatory Activity |
| title_full_unstemmed | Artocarpus hirsutus Lam Leaf Extract-Evaluation of Analgesic and Anti-Inflammatory Activity |
| title_short | Artocarpus hirsutus Lam Leaf Extract-Evaluation of Analgesic and Anti-Inflammatory Activity |
| title_sort | artocarpus hirsutus lam leaf extract evaluation of analgesic and anti inflammatory activity |
| url | http://dx.doi.org/10.1155/2022/4179487 |
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