Psychosocial behavioral phenotypes of racially/ethnically minoritized older adults enrolled in HABS‐HD differ on neuroimaging measures of brain age gap, hippocampal volume, and cortical thickness

Psychosocial behavioral phenotypes of racially/ethnically minoritized older adults enrolled in HABS‐HD differ on neuroimaging measures of brain age gap, hippocampal volume, and cortical thickness

Abstract INTRODUCTION This study examined whether previously identified psychosocial behavioral phenotypes differed on structural neuroimaging markers. METHODS Latent profile analysis (LPA) employed in a sample of 1820 community‐dwelling older adults (1118 Hispanic and 702 Black) replicated previous...

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Main Authors: Alexandra L. Clark, Makenna B. McGill, Alexandra J. Weigand, Julie K. Wisch, Kalen Petersen, Beau Ances, Meredith N. Braskie, Sid O'Bryant, Kelsey R. Thomas, HABS‐HD Study Team
Format: Article
Language:English
Published: Wiley 2025-04-01
Series:Alzheimer’s & Dementia: Translational Research & Clinical Interventions
Subjects:
brain age gap
health disparities
hippocampal volume
neurodegeneration
neuroimaging
phenotyping
Online Access:https://doi.org/10.1002/trc2.70109
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