Der Übergangszustand der bimolekularen Eliminierung (E2-Reaktion) aufgrund neuerer kinetischer Isotopeneffektstudien
A discussion of the concerted E2 mechanism is presented with special emphasis on the model of the variable transition state. Sufficient evidence for the concertedness is based on primary β-hydrogen and α-heavy atom kinetic isotope effects. For various E2 reactions, results of experimental studies o...
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| Format: | Article |
| Language: | deu |
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Swiss Chemical Society
1977-03-01
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| Series: | CHIMIA |
| Online Access: | https://www.chimia.ch/chimia/article/view/9344 |
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| Summary: | A discussion of the concerted E2 mechanism is presented with special emphasis on the model of the variable transition state. Sufficient evidence for the concertedness is based on primary β-hydrogen and α-heavy atom kinetic isotope effects. For various E2 reactions, results of experimental studies of primary β-H and α-N as well as secondary α-H and hydroxide-H isotope effects are compiled. Conclusions are drawn concerning the effect of reactant structure on relative degrees of Cα-X and Cβ-H bond breaking in the transition state. Special attention is given to the influence of remote substituents on the transition state geometry. The findings are discussed with the aid of a qualitative model of the potential energy surface.
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| ISSN: | 0009-4293 2673-2424 |