The Role of Optic Nerve Sheath Diameter in Differential Diagnosis in Patients with Headache, A Prospective, Randomized Controlled Study

Objective: This study aimed to evaluate the usability of the optic nerve sheath diameter (ONSD) in the differential diagnosis of headache. Materials and Methods: This study included non-traumatic patients with headache. Patients were divided into three groups. Primary headache was assigned to group...

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Main Authors: Ayşegül İşlek Yüksel, Fatih Selvi, Serkan Yüksel, Mustafa Avcı, Gülsüm Çalışkan Günay, Nalan Kozacı
Format: Article
Language:English
Published: Türkiye Acil Tıp Vakfı 2025-04-01
Series:Global Emergency and Critical Care
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Online Access:https://globemcc.com/articles/the-role-of-optic-nerve-sheath-diameter-in-differential-diagnosis-in-patients-with-headache-a-prospective-randomized-controlled-study/doi/globecc.galenos.2024.91300
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author Ayşegül İşlek Yüksel
Fatih Selvi
Serkan Yüksel
Mustafa Avcı
Gülsüm Çalışkan Günay
Nalan Kozacı
author_facet Ayşegül İşlek Yüksel
Fatih Selvi
Serkan Yüksel
Mustafa Avcı
Gülsüm Çalışkan Günay
Nalan Kozacı
author_sort Ayşegül İşlek Yüksel
collection DOAJ
description Objective: This study aimed to evaluate the usability of the optic nerve sheath diameter (ONSD) in the differential diagnosis of headache. Materials and Methods: This study included non-traumatic patients with headache. Patients were divided into three groups. Primary headache was assigned to group 1, secondary headache to group 2, and healthy volunteers to group 3. ONSD was measured by ultrasonography before computed cranial tomography imaging. Results: A total of 50 patients in groups 1 and 2 and 50 healthy volunteers in group 3 were included. The mean ONSD of healthy volunteers was 4.2 mm, and the mean ONSD difference between eyes was 0.2 mm. The mean ONSD for the primary headache was 4.5 mm, and the mean ONSD difference for both eyes was 0.2 mm. The ONSD of the secondary headache was measured as 6.2 mm, and the ONSD difference between the eyes was 0.3 mm. The ONSD difference in both eyes and the ONSD of patients with secondary headache were higher than those in groups 1 and 3 (p<0.001). The ONSD cutoff value, which was positive on CT imaging, was 5.2 mm. Conclusion: The ONSD and difference in ONSD can be used in the differential diagnosis of primary and secondary headache.
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institution Kabale University
issn 2822-4078
language English
publishDate 2025-04-01
publisher Türkiye Acil Tıp Vakfı
record_format Article
series Global Emergency and Critical Care
spelling doaj-art-a36b507ecf5e435fb087581d3960d4b42025-08-20T03:52:32ZengTürkiye Acil Tıp VakfıGlobal Emergency and Critical Care2822-40782025-04-0141232910.4274/globecc.galenos.2024.91300The Role of Optic Nerve Sheath Diameter in Differential Diagnosis in Patients with Headache, A Prospective, Randomized Controlled StudyAyşegül İşlek Yüksel0https://orcid.org/0000-0002-3524-1758Fatih Selvi1https://orcid.org/0000-0002-9701-9714Serkan Yüksel2https://orcid.org/0000-0002-6165-6455Mustafa Avcı3https://orcid.org/0000-0002-5018-9070Gülsüm Çalışkan Günay4https://orcid.org/0000-0001-8660-8970Nalan Kozacı5https://orcid.org/0000-0001-7758-3839Kahta State Hospital, Clinic of Emergency Medicine, Adıyaman, TürkiyeUniversity of Health Sciences Türkiye, Antalya Training and Research Hospital, Clinic of Emergency Medicine, Antalya, TürkiyeKahta State Hospital, Clinic of Radiology, Adıyaman, TürkiyeUniversity of Health Sciences Türkiye, Antalya Training and Research Hospital, Clinic of Emergency Medicine, Antalya, TürkiyeAtatürk State Hospital, Clinic of Emergency Medicine, Antalya, TürkiyeAlanya Alaaddin Keykubat University, Alanya Training and Research Hospital, Clinic of Emergency Medicine, Antalya, TürkiyeObjective: This study aimed to evaluate the usability of the optic nerve sheath diameter (ONSD) in the differential diagnosis of headache. Materials and Methods: This study included non-traumatic patients with headache. Patients were divided into three groups. Primary headache was assigned to group 1, secondary headache to group 2, and healthy volunteers to group 3. ONSD was measured by ultrasonography before computed cranial tomography imaging. Results: A total of 50 patients in groups 1 and 2 and 50 healthy volunteers in group 3 were included. The mean ONSD of healthy volunteers was 4.2 mm, and the mean ONSD difference between eyes was 0.2 mm. The mean ONSD for the primary headache was 4.5 mm, and the mean ONSD difference for both eyes was 0.2 mm. The ONSD of the secondary headache was measured as 6.2 mm, and the ONSD difference between the eyes was 0.3 mm. The ONSD difference in both eyes and the ONSD of patients with secondary headache were higher than those in groups 1 and 3 (p<0.001). The ONSD cutoff value, which was positive on CT imaging, was 5.2 mm. Conclusion: The ONSD and difference in ONSD can be used in the differential diagnosis of primary and secondary headache.https://globemcc.com/articles/the-role-of-optic-nerve-sheath-diameter-in-differential-diagnosis-in-patients-with-headache-a-prospective-randomized-controlled-study/doi/globecc.galenos.2024.91300computed cranial tomographyemergency medicineheadacheoptic nerve sheath diameterultrasonography
spellingShingle Ayşegül İşlek Yüksel
Fatih Selvi
Serkan Yüksel
Mustafa Avcı
Gülsüm Çalışkan Günay
Nalan Kozacı
The Role of Optic Nerve Sheath Diameter in Differential Diagnosis in Patients with Headache, A Prospective, Randomized Controlled Study
Global Emergency and Critical Care
computed cranial tomography
emergency medicine
headache
optic nerve sheath diameter
ultrasonography
title The Role of Optic Nerve Sheath Diameter in Differential Diagnosis in Patients with Headache, A Prospective, Randomized Controlled Study
title_full The Role of Optic Nerve Sheath Diameter in Differential Diagnosis in Patients with Headache, A Prospective, Randomized Controlled Study
title_fullStr The Role of Optic Nerve Sheath Diameter in Differential Diagnosis in Patients with Headache, A Prospective, Randomized Controlled Study
title_full_unstemmed The Role of Optic Nerve Sheath Diameter in Differential Diagnosis in Patients with Headache, A Prospective, Randomized Controlled Study
title_short The Role of Optic Nerve Sheath Diameter in Differential Diagnosis in Patients with Headache, A Prospective, Randomized Controlled Study
title_sort role of optic nerve sheath diameter in differential diagnosis in patients with headache a prospective randomized controlled study
topic computed cranial tomography
emergency medicine
headache
optic nerve sheath diameter
ultrasonography
url https://globemcc.com/articles/the-role-of-optic-nerve-sheath-diameter-in-differential-diagnosis-in-patients-with-headache-a-prospective-randomized-controlled-study/doi/globecc.galenos.2024.91300
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